Cationic phospholipids for transfection

Details Cationic phospholipids for transfection Cationic phospholipids for transfection

1995-06-06

1999-04-06

Campell, Bruce R.

Chemistry: molecular biology and microbiology

Vector, per se

435455, 435325, 424450, 246 41, 514 44, 536 231, 536 245, 558 70, 558166, 564 15, C12N 1563

Patent

active

058917144

ABSTRACT:
Cationic phospholipids and their use in treating pathogen-associated disease are disclosed. The class of phospholipids comprises the phosphotriester derivatives of phosphoglycerides and sphingolipids. Liposomes comprising one or more of the cationic phospholipids are effective in the lipofection of nuclidic acids and are therefore useful in methods of treating disease.

REFERENCES:
patent: 4480041 (1984-10-01), Myles et al.
patent: 4493832 (1985-01-01), Teraji et al.
patent: 4562179 (1985-12-01), Teraji et al.
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 4946787 (1990-08-01), Eppstein et al.
patent: 4948576 (1990-08-01), Verdicchio et al.
patent: 5153347 (1992-10-01), Lloyd
patent: 5344930 (1994-09-01), Riess et al.
patent: 5420330 (1995-05-01), Brush
patent: 5585479 (1996-12-01), Holze et al.
patent: 5661018 (1997-08-01), Ashley et al.
Coghlan, New Scientists, vol. 148:14-15, 1995.
Wagner, Nature, 372:333-335, 1994.
Stull et al., Pharmaceutical Res., 12:465-483, 1995.
Wu-Pong, Pharmaceutical Technology, Oct. 1994, 103-114, 1994.
Felgner et al. Lipofection: A Highly Efficient--PNAS 84:7413-7417, 1987.
Graham and Van der Eb, Virology 52, 456 (1973).
Kawai and Nishizawa, Mol. Cell Biol. 4, 1172 (1984).
Neumann et al., EMBO Journal 1, 841 (1982).
Graessmann and Graessmann in Microinjection and Organelle Transplantation Techniques, pp. 3-13 (Cells et al., Eds., Academic Press 1986).
Cudd and Nicolau, in Liposome Technology, pp. 207-221 (G. Gregoriadis, Ed., CRC Press 1984)
Cepko et al., Cell 37, 1053 (1984).
Schaffner, Proc. Natl. Acad. Sci. USA 77, 2163 (1980).
Magee et al., Biochim. Biophys. Acta 451, 610-618 (1976).
Straub et al., Infect. Immun. 10, 783-792 (1974).
Martin and MacDonald, J. Cell Biol. 70, 515-526 (1976).
Magee et al., J. Cell. Biol. 63, 492 (1974).
Steger and Desnick, Biochim. Biophys. Acta, 464, 530 (1977).
Juliano and Stamp, Biochem. Pharma. 27, 21-27 (1978).
Mayhew et al., Cancer Res. 36, 4406 (1976).
Kimelberg, Biochim. Biophys. Acta 448, 531 (1976).
Thierry et al. in Gene Regulation: Biology of Antisense RNA and DNA, p. 147 (Erickson and Izant, Eds., Raven Press, New York, 1992).
Hug and Sleight, Biochim. Biophys. Acta 1097, 1 (1991).
Nicolau and Cudd, Crit. Rev. Ther. Drug Carr. Sys. 6, 239 (1989).
Senior et al., Biochim. Biophys. Acta 1070, 173 (1991).
Felgner et al., Proc. Natl. Acad. Sci. USA 84, 7413 (1987).
Rose et al., BioTechniques 10, 520 (1991).
Malone et al., Proc. Natl. Acad. Sci. USA 86, 6077 (1989).
Zhou and Haung, J. Controlled Release 19, 269 (1992).
Hawley-Nelson et al., Focus. 15, 73 (1990, BRL publications).
Farhood et al., Biochim. Biophys. Acta 1111, 239 (1992).
Gao and Huang, Biochim. Biophys. Res. Comm. 179, 280 (1991).
Holt et al., Neuron 4, 203 (1990).
Malone, Focus 11, 4 (1989, BRL publications).
Ono et al., Neurosci. Lett. 117, 259 (1990).
Brigham et al., Am. J. of Med. Sci. 298, 278 (1989).
Nabel et al., Science 249, 1285 (1990).
Lim et al., Circulation 83, 2007 (1991).
Hazinski, Sem. Perinatol. 16, 200 (1992).
Yosimura et al., Nucleic Acids Res. 20, 3233 (1992).
Hyde et al., Nature 362, 250 (1993).
Ballas et al., Biochim. et Biophys. Acta 939, 8 (1988).
Pinnaduwage et al., Biochim. et Biophys. Acta 985, 33 (1989).
Taylor et al., Nucleic Acids Res. 20, 4559-4565 (1992).
Leventis and Sivius, Biochim. et Biophys. Acta 1023, 124 (1990).
Duzgunes and Felgner, Methods in Enzymology 221, 303 (1993).
Smith et al., Biochim. Biophys. Acta 1154, 327 (1993).
Maccarrone et al., Biochem. Biophys. Res. Comm. 186, 1417 (1992).
Gershon et al., Biochem. 32, 7143-7151 (1993).
Legendre and Szoka, Pharm. Res. 9, 1235 (1992).
Renkonen, Biochim. et Biophys. Acta 152, 114 (1968).
Gorman et al., Mol. Cell. Biol. 2, 1044 (1982).
de Wet et al., Mol. Cell. Biol. 7, 725 (1987).
Jarnagin et al., Nucl. Acids Res. 20, 4205 (1992).
Zhu et al., Science 261, 209-211 (1993).
Stribling et al., Proc. Natl. Acad. Sci. USA 89, 11277-11281 (1992).
Chemical Abstracts 73:310, Abstract No. 024844 (1970).
Chen, J.-S. and Barton, P.G., Can. J. Biochem. 48:585-593 (1970).
Liposome Technology, vol. 1, Chapter 1, pp. 1-37 (G. Gregoriadis, Ed., CRC Press, 1993).
Liposome Technology, vol. 1, Chapter 3, pp. 49-65 (G. Gregoriadis, Ed., CRC Press, 1993).
Liposome Technology, vol. 1, Chapter 27, pp. 487-499 (G. Gregoriadis, Ed., CRC Press, 1993).
Liposome Technology, vol. 1, Chapter 28, pp. 501-525 (G. Gregoriadis, Ed., CRC Press, 1993).
Booklet from Nov. 1, 1991 Northwestern University Chemistry Department Fall Symposium, entitled "Advances in Nucleic Acids Chemistry".
List of Posters presented at Nov. 1, 1991 Northwestern University Chemistry Department Fall Symposium, entitled "Advances in Nucleic Acids Chemistry".
Abstract of Poster by Gary W. Ashley, Miho Shida and Robert MacDonald, presented at Nov. 1, 1991 Northwestern University Chemistry Department Fall Symposium.
Bruzik et al., J. Org. Chem. 51:2368-2370 (1986).
Qiu, X. et al., J. Org. Chem. 59:537-543 (1994).
Law, S-J. et al., Tetrahedron Letters 27:271-274 (1986).

Affiliated with

Also associated with

Rating

Cationic phospholipids for transfection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cationic phospholipids for transfection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cationic phospholipids for transfection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1370666