Cationic lipids and use thereof

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Cyclopentanohydrophenanthrene ring system doai

Reexamination Certificate

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Reexamination Certificate

active

07550452

ABSTRACT:
The present invention relates to cationic lipids, methods for preparing some and methods for effectively transporting anionic molecular substances into cell by using said cationic lipids. The present lipids are compatible to gene therapy due to their stability and highly transporting effects.

REFERENCES:
patent: 5908635 (1999-06-01), Thierry
patent: 5994317 (1999-11-01), Wheeler
patent: 6056938 (2000-05-01), Unger et al.
patent: 6110490 (2000-08-01), Thierry
patent: WO 93/05162 (1993-03-01), None
The Osgood File( CBS Radio Network, 2004); AFCNEWSOURCE: Fireflies and Cancer; pp. 1-3.
Zhang, Yuanpeng; Lipid particles having asymmetric lipid coating and method of preparing same, 2003, FreshPatents.com,#20060165770, pp. 1-20.
Ghosh et al., Advanatage of the Ether Linkage between the Positive Charge and the Cholesteryl Skeleton in Cholesterol-Based Amphiphiles as Vectors for Gene Delivery,(2001-2002), Bioconjugate Chem. (2002), 13, 378-384.
Bhattacharya et al., The effects of cholesterol inclusion on the vesicular membranes of cationic lipids, Department of Organic Chemistry, Indian Institute of Science, Bangalore, 560 012, India, Biochimica et Biophysica Acta, Biomembranes (1996), 1283(1), 21-30 (Abstract Only).
Bhattacharya et al., Synthesis, Thermotropic Behavior, and Permeability Porperties of Vesicular Mebranes Composed of Cationic Mixed-Cahin Surfactants, Department of Organic Chemistry, Indian Institute of Science, Bangalore, IA, 560012, India Langmuir (1995), 11(12), 4748-57 (Abstract Only).
Abid et al., Synthesis of polymerizable and non-polymerizable liquid-crystalline vesicle-forming quaternary ammonium derivatives of cholesterol, Dep. Pure and Appl. Chem., Univ. Strathclyde, Glasgow, G1, 1XL, UK, Polymer Communications (1987), 28(1), 16-19 (Abstract Only).
Yamuna Krishnan Ghosh, Sandhya S. Visweswariah, and Santanu Bhattacharya, Nature of Linkage Between the Cationic Headgroup and Cholesteryl Skeleton Controls Gene Transfection Efficiency, FEBS Letters 473 (2000), Apr. 14, 2000, pp. 341-344.
Santanu Bhattacharya and Yamuna Krishnan-Ghosh, Vesicle Formation from Oligo (oxyethylene)-Bearing Cholesteryl Amphiphiles: Site-Selective Effects of Oxygethylene Units on the Membrane Order and Thickness, Langmuir 2001, vol. 17, Jun. 29, 2000, pp. 2067-2075.
Amanda J. Bradley, Dana V. Devine, Steven M. Answell, Johan Janzen, and Donald E. Brooks, Inhibition of Liposome-Induced Complement Activation by Incorporated Poly(Ethylene Glycol)-Lipids, Archives of Biochemistry and Biophysics, vol. 357, No. 2, Sep. 15, 1998, pp. 185-194.
Elizabeth G. Nabel, Gregory Plautz, and Gary J. Nabel, Site-Specific Gene Expression in Vivo by Direct Gene Transfer into the Arterial Wall, Science, vol. 249, Sep. 14, 1990, pp. 1285-1288.
Philip L. Felgner, Thomas R. Gadek, Marilyn Holm, Richard Roman, Hardy W. Chan, Michael Wenz, Jeffrey P. Northrop, Gordon M. Ringold, and Mark Danielsen, Lipofection: A Highly Efficient, Lipid-Mediated DNA-Transfection Procedure, Proc. Natl. Acad. Sci. USA, vol. 84, Nov. 1987, pp. 7413-7417.
Chen-Yen Wang and Leaf Huang, pH-Sensitive Immunoliposomes Mediate Target-Cell-Specific Delivery and Controlled Expression of a Foreign Gene in Mouse, Proc. Natl. Acad. Sci. USA, vol. 84, Nov. 1987, pp. 7851-7855.
Various Book Reviews, Nature, vol. 338, Mar. 30, 1989, pp. 337-338.
Philip L. Felgner, Particulate Systems and Polymers for In Vitro and In Vivo Delivery of Polynucleotides, Advanced Drug Delivery Reviews, vol. 5, May 5, 1990, pp. 163-187.

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