Organic compounds -- part of the class 532-570 series – Organic compounds – Fatty compounds having an acid moiety which contains the...
Reexamination Certificate
2005-06-07
2010-06-29
Kelly, Robert M (Department: 1633)
Organic compounds -- part of the class 532-570 series
Organic compounds
Fatty compounds having an acid moiety which contains the...
C424S009510, C424S450000, C554S105000, C554S108000, C554S110000, C554S127000, C514S04400A
Reexamination Certificate
active
07745651
ABSTRACT:
The present invention provides compositions comprising cationic lipids, liposomes and nucleic acid-lipid particles comprising the cationic lipids, and methods of using such compositions, liposomes, and nucleic acid-lipid particles.
REFERENCES:
patent: 4394448 (1983-07-01), Szoka, Jr. et al.
patent: 4438052 (1984-03-01), Weder et al.
patent: 4515736 (1985-05-01), Deamer
patent: 4598051 (1986-07-01), Papahadjopoulos et al.
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 5013556 (1991-05-01), Woodle et al.
patent: 5171678 (1992-12-01), Behr et al.
patent: 5208036 (1993-05-01), Eppstein et al.
patent: 5225212 (1993-07-01), Martin et al.
patent: 5264618 (1993-11-01), Felgner et al.
patent: 5279833 (1994-01-01), Rose
patent: 5283185 (1994-02-01), Epand et al.
patent: 5320906 (1994-06-01), Eley et al.
patent: 5545412 (1996-08-01), Eppstein et al.
patent: 5578475 (1996-11-01), Jessee et al.
patent: 5641662 (1997-06-01), Debs et al.
patent: 5656743 (1997-08-01), Busch et al.
patent: 5703055 (1997-12-01), Felgner et al.
patent: 5705385 (1998-01-01), Bally et al.
patent: 5820873 (1998-10-01), Choi et al.
patent: 5976567 (1999-11-01), Wheeler et al.
patent: 5981501 (1999-11-01), Wheeler et al.
patent: 6534484 (2003-03-01), Wheeler et al.
patent: 6586410 (2003-07-01), Wheeler et al.
patent: 6649780 (2003-11-01), Eibl et al.
patent: 6815432 (2004-11-01), Wheeler et al.
patent: 6858224 (2005-02-01), Wheeler et al.
patent: 2003/0077829 (2003-04-01), MacLachlan
patent: 2003/0125263 (2003-07-01), Gold et al.
patent: 2003/0143732 (2003-07-01), Fosnaugh et al.
patent: 2004/0063654 (2004-04-01), Davis et al.
patent: 2004/0142892 (2004-07-01), Finn et al.
patent: 2004/0253723 (2004-12-01), Tachas et al.
patent: 2004/0259247 (2004-12-01), Tuschl et al.
patent: 2006/0105976 (2006-05-01), Soutschek et al.
patent: WO 91/16024 (1991-10-01), None
patent: WO 93/05162 (1993-03-01), None
patent: WO 93/12240 (1993-06-01), None
patent: WO 93/12756 (1993-07-01), None
patent: WO 93/24640 (1993-12-01), None
patent: WO 93/25673 (1993-12-01), None
patent: WO 95/02698 (1995-01-01), None
patent: WO 95/18863 (1995-07-01), None
patent: WO 95/35301 (1995-12-01), None
patent: WO 96/02655 (1996-02-01), None
patent: WO 96/10390 (1996-04-01), None
patent: WO 96/41873 (1996-12-01), None
patent: WO 01/05374 (2001-01-01), None
patent: WO 02/34236 (2002-05-01), None
patent: WO 02/087541 (2002-11-01), None
patent: WO 03/097805 (2003-11-01), None
patent: WO 2004/065546 (2004-08-01), None
patent: WO 2004/110499 (2004-12-01), None
patent: WO 2005/007196 (2005-01-01), None
patent: WO 2005/026372 (2005-03-01), None
patent: WO 2005/120152 (2005-12-01), None
Arpicco et al., 1999, Proceed. Int'l Symp. Control. Rel. Bioact. Mater. 26:7759-760 (+face page).
Ballas, N. et al., “Liposomes bearing a quartemary ammonium detergent as an efficient vehicle for functional transfer of TMV-RNA into plant protoplasts,”Biochim. Biophys. Acta,1998, pp. 8-18, vol. 939.
Barinaga, M., “Step Taken Toward Improved Vectors for Gene Transfer,”Science,1994, p. 1326, vol. 266.
Behr, J-P., “Synthetic Gene-Transfer Vectors,”Acc. Chem. Res.1993, pp. 274-278, vol. 26.
Brigham, K. et al., “Rapid Communication: In vivo Transfection of Murine Lungs with a Functioning Prokaryotic Gene Using a Liposome Vehicle,”Am. J. Med. Sci.,1989, pp. 278-281, vol. 298.
Cortesi, R., et al.. “Effect of cationic liposome composition on in vitro cytotoxicity and protective effect on carried DNA,”International Journal of Pharmaceutics,1996, pp. 69-78, vol. 139.
Crystal, R., “Transfer of Genes to Humans: Early Lessons and Obstacles to Success,”Science,1995, pp. 404-410, vol. 270.
Culver K.,, “The First Human Gene Therapy Experiment,”Gene Therapy: A Handbook for Physicians,1994, pp. 33-40.
Duzgunes, N., “Membrane Fusion,”Subcellular Biochemistry,1985, pp. 195-286, vol. 11.
Dwarki, V.J., et al., “Cationic Liposime-Mediated RNA Transfection.”Methods in Enzymology,1993, pp. 644-654, vol. 217.
Enoch, H. et al., “Formation and properties of 1000-Å-diameter, single-bilayer phospholipid vesicles,”Proc. Natl. Acad. Sci. USA,1979, pp. 145-149, vol. 76, No. 1.
Felgner, P. et al., “Lipofection: A highly efficient, lipid-mediated DNA-transfection procedure,”Proc. Natl. Acad. Sci. USA,1987, pp. 7413-7417, vol. 84.
Felgner, J.H., et al., “Enhanced Gene Delivery and Mechanism Studies with a Novel Series of Cationic Lipid Formulations,”The Journal of Biological Chemistry,Jan. 1994, pp. 2550-2561, vol. 269, No. 4.
Felgner, J., et al., “Cationic Lipid-Mediated Transfection in Mammalian Cells: “Lipofection”,”J. Tiss. Cult. Meth.,1993, pp. 63-68, vol. 15.
Felgner, P.L., et al., “Cationic Liposome Mediated Transfection,”Proc. West. Pharmacol. Soc.,1989, pp. 115-121, vol. 32.
Gao, X. et al., “A Novel Cationic Liposome Reagent for Efficient Transfection of Mammalian Cells,”Biochem. Biophys. Res. Comm.,1991, pp. 280-285, vol. 179.
Gershon, H. et al., “Mode of Formation and Structural Feature of DNA-Cationic Liposome Complexes Used for Transfection,”Biochemistry,1993, pp. 7413-7151, vol. 32.
Guy-Caffey, J., et al., “Novel Polyaminolipids Enhance the Cellular Uptake of Oligonucleotides,”The Journal of Biological Chemistry,Dec. 1995, pp. 31391-31396, vol. 270, No. 52.
Hawley-Nelson, et al., “LipofectAmine™ Reagent: A New, Higher Efficiency Polycationic Liposome Transfection Reagent,”Focus,1993, p. 73-80, vol. 15, No. 3.
Hyde, S., et al., “Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy,”Nature,1993, pp. 250-256, vol. 362.
Jiang, Lei et al.; “Comparison of protein precipitation methods for sample preparation prior to proteomic analysis”; 2004,Journal of Chromatography,vol. 1023, No. 2, pp. 317-320.
Juliano R., and Stamp, D., “The Effect of Particle Size and Charge on the Clearance Rates of Liposomes and Liposome Encapsulated Drugs,”Biochem. Biophys. Res. Commun.,1975, pp. 651-658, vol. 63.
Legendre, J.Y. and Szoka, F., “Delivery of Plasmid DNA into Mammalian Cell Lines Using pH-Sensitive Liposomes: Comparison with Cationic Liposomes,”Pharm. Res.,1992, pp. 1235-1242, vol. 9, No. 10.
Leventis, R., et al.,, “Interactions of mammalian cells with lipid dispersions containing novel metabolizable cationic amphiphiles,”Biochem. Blophys. Acta,1990, p. 124, vol. 1023.
Marshall, E., “Gene Therapy's Growing Pains,”Science,1995, pp. 1050-1055. vol. 269.
Orkin, et al.,NIH Report, Report and Recommendations of the Panel to Assess the NIH Investment in Research on Gene Therapy,1995.
Paul, Cynthia P. et al.; “Effective expression of small Interfering RNA in human cells”; 2002,Nature Biotechnology,vol. 20, pp. 505-508.
Puyal, C., et al., “A new cationic liposome encapsulating genetic material: A potential delivery system for polynucleotides,”Eur. J. Biochem.,1995, pp. 697-703, vol. 228.
Spagnou, Sebastien et al.; “Lipidic Carriers of siRNA: Differences in the Formulation, Cellular Uptake, and Delivery with Plasmid DNA”; 2004,Biochemistry,vol. 43, pp. 13348-13356.
Stamatatos, L, et al., “Interactions of Cationic Lipid Vesicles with Negatively Charged Phospholipid Vesicles and Biological Membranes,”Biochemistry,1988, pp. 3917-3925, vol. 27.
Szoka, F. et al., “Comparative Properties and Methods of Preparation of Lipid Vesicles (Liposomes),”Ann. Rev. Biophys. Bioeng.,1980, pp. 467-508, vol. 9.
Szoka, F. et al., “Procedure for preparation of liposomes with large internal aqueous space and high capture by reverse-phase evaporation,”Proc. Natl. Acad. Sci. USA,1978, pp. 4194-4198, vol. 75, No. 9.
Van Der Woude, I., et al., “Parameters influencing the Introduction of plasmid DNA into cells by the use of synthetic amphiphiles as a carrier system,
Heyes James
MacLachlan Ian
Palmer Lorne R.
Hiriyanna Kelaginamane
Kelly Robert M
Protiva Biotherapeutics Inc.
Townsend and Townsend / and Crew LLP
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