Organic compounds -- part of the class 532-570 series – Organic compounds – Amino nitrogen containing
Patent
1992-08-28
1994-08-02
Raymond, Richard L.
Organic compounds -- part of the class 532-570 series
Organic compounds
Amino nitrogen containing
554105, 554106, 554107, 560222, 560251, 564292, 564504, 206569, C07C23336
Patent
active
053347617
ABSTRACT:
The present invention discloses cationic lipids useful for making lipid aggregates for delivery of macromolecules and other compounds into cells. They are especially useful for the DNA-dependent transformation of cells. Also disclosed are lipids useful both for the delivery of macromolecules and also useful as intermediates for making other such lipids.
REFERENCES:
patent: 4897355 (1990-01-01), Eppstein et al.
patent: 5889953 (1989-12-01), Inoue et al.
Felgner et al. (1987) Proc. Natl. Acad. Sci. USA 84:7413-7417.
Zhou et al. (1991) Biochim. Biophys. Acta 1065:8-14.
Chytil Anna
Ciccarone Valentina C.
Gebeyehu Gulilat
Hawley-Nelson Pamela
Jessee Joel A.
Life Technologies Inc.
Raymond Richard L.
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