Cationic lipid DNA complexes for gene targeting

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Liposomes

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4353201, 435455, 435458, A61K 9127, C12N 500, C12N 1500

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059322411

ABSTRACT:
This invention herein describes pharmaceutical compositions and methods for targeted delivery of functional genes into cells and tissues in vivo. The invention discloses DNA:lipid complexes, methods of making such complexes and methods of using such complexes for facilitating the targeted delivery and entry of recombinant expression constructs into cells and tissues in vivo, and particularly delivery of such recombinant expression constructs to lung cells and tissues.

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