Cationic lipid compositions targeting angiogenic endothelial cel

Details Cationic lipid compositions targeting angiogenic endothelial cel Cationic lipid compositions targeting angiogenic endothelial cel

1998-07-31

2000-09-19

Kishore, Gollamudi S.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Liposomes

935 54, A61K 9127

Patent

active

061207993

ABSTRACT:
Angiogenic endothelial cells are selectively targeted with lipid/DNA complexes or cationic liposomes containing a substance which affects the targeted cells by inhibiting or promoting their growth. A site of angiogenesis can be precisely located by administering cationic liposomes containing a detectable label. The complexes may comprise nucleotide constructs which are comprised of promoters which are selectively and exclusively activated in the environment of an angiogenic endothelial cell.

REFERENCES:
patent: 5264618 (1993-11-01), Felgner et al.
patent: 5641755 (1997-06-01), Weichselbaum
patent: 5770581 (1998-06-01), Weichselbaum
patent: 5830880 (1998-11-01), Sedlacek et al.
patent: 5837682 (1998-11-01), Folkman
patent: 5885833 (1999-03-01), Mueller et al.
Teifel et al., "Optimization of Transfection of Human Endothelial Cells," Endothelium, 3:21-35 (1997).

Affiliated with

Also associated with

Rating

Cationic lipid compositions targeting angiogenic endothelial cel does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cationic lipid compositions targeting angiogenic endothelial cel, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cationic lipid compositions targeting angiogenic endothelial cel will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1069644