Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...
Patent
1983-04-15
1985-07-02
Nucker, Christine M.
Drug, bio-affecting and body treating compositions
Radionuclide or intended radionuclide containing; adjuvant...
424 9, 568 2, 568 8, 568 13, 568 14, 568 15, 568 16, 568 17, 534 14, A61K 4300, A61K 4900
Patent
active
045267766
ABSTRACT:
An hepatobiliary imaging agent is disclosed which is a cationic complex of Tc-99m, a cyanate or thiocyanate ion, and a mono or polydentate organic ligand having one or more donor atoms, each with a free-electron pair available for accepting a proton or for complexing with Tc-99m to form a cationic complex. These complexes can provide images of the hepatobiliary transit in as little as ten minutes.
REFERENCES:
patent: 2587805 (1952-03-01), Akobjanoff
patent: 3188345 (1965-06-01), Burg et al.
patent: 3478035 (1969-11-01), Barrett
patent: 3478036 (1969-11-01), Winkelmann et al.
patent: 3695853 (1972-10-01), Klanberg
patent: 3798241 (1974-03-01), Kagan et al.
patent: 3819670 (1974-06-01), Kemp
patent: 4133872 (1979-01-01), Schmidt-Dunker et al.
patent: 4247534 (1981-01-01), Bevan
patent: 4338248 (1982-07-01), Yokoyama et al.
patent: 4363793 (1982-12-01), Blau et al.
patent: 4374821 (1983-02-01), Glavan et al.
Friesen, D. K. et al., J. of Molecular Structure, 31, (1976), 77-95.
Communications to the Editor, J. Am. Chem. Soc., 1980, vol. 102, No. 22, 1980, pp. 6849-6851.
Zsuzsa Nagy-Magos et al., J. of Organometallic Chemistry, 171, (1979), 97-102.
Akhtar, M. et al., Inorganic Chemistry, vol. 11, No. 12, 1972, pp. 2917-2921.
Communications to the Editor, J. Am. Soc., 101, 1979, pp. 1053-1054.
Brown, L. D. et al., Inorganic Chemistry, vol. 17, No. 3, 1978, pp. 729-734.
Albright, J. O. et al., J. Am. Chem. Soc., 101, (1979), 611-619.
Kyba, E. P. et al., J. Am. Chem. Soc., vol. 102, No. 23, 1980, pp. 7012-7014.
Butter, S. A. et al., J. Am. Chem. Soc., (1970), pp. 1411-1415.
Inoue, Y. et al., Bulletin of the Chem. Soc. of Japan, vol. 51(B), (1978), pp. 2375-2378.
Chatt, J. et al., J. Chem. Soc., (1961), pp. 896-904, (1962), pp. 2545-2549.
Mazzi, U. et al., Inorganic Chemistry, vol. 16, No. 5, 1977, pp. 1042-1048.
Ferguson, J. E. et al., Aust. J. Chem., 1970, 23, 453-61.
King, R. B., Acc. Chem. Res., 1980, 13, pp. 243-248.
Curtis, N. F., Chemistry and Industry, May 24, 1958, pp. 625-626.
Communications to the Editor, J. Am. Chem. Soc., 97, (1975), pp. 1955-1956.
Bandoli, G. et al., J. C. S. Dalton, (1976), pp. 125-130.
Wymore, C. E. et al., J. Inorg. Nucl. Chem., 1960, vol. 14, pp. 42-54.
Ferguson, J. E. et al., J. Inorg. Nucl. Chem., 1966, vol. 28, pp. 2293-2296.
Cooper, P. et al., J. Chem. Soc., (C) (1971), pp. 3031-3035.
Subramanian, Gopal et al., Proceedings of the 28th Annual Meeting, Los Vegas, Jun. 16-19, 1981, vol. 22, No. 6, p. 51.
Deutsch, E. et al., Science, vol. 214, (1981), pp. 85-86.
Ferguson, J. E. et al., Chemistry and Industry, Nov. 22, 1958, p. 1555.
Viard, B., J. Inorg. Nucl. Chem., 1977, vol. 39, pp. 1090-1092.
Fergusson et al., Chemistry and Industry, pp. 347, 348.
Deutsch et al, J. Nucl. Med., vol. 22, (Oct. 1981); 897-907.
Rajeckas Algis
Subramanyam Vinayakam
Bronstein Sewall P.
E. I. du Pont de Nemours & Company
Neuner George W.
Nucker Christine M.
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