Cationic compounds useful for making radiodiagnostic agents

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant...

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260429R, 260440, 260446, 568 2, 568 8, 568 13, 568 14, 568 15, 568 16, 568 17, 424 9, A61K 4300, A61K 4900, C07F 966, C07F 990

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044514506

ABSTRACT:
A normally solid, hydrophilic compound capable of binding with Tc-99m to form a cationic complex is provided. The compound has a formula selected from: ##STR1## wherein: R, R', R", R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are each independently selected from hydrogen; or substituted or unsubstituted alkyl, alkylene, aryl, alkylaryl, arylalkyl, monocycloalkyl, polycycloalkyl, heterocyclic and carbocyclic groups; and R plus R.sup.i in formula (A) may be taken together to form a cyclic compound;

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