Cationic compounds and their use as macro molecular carriers

Details Cationic compounds and their use as macro molecular carriers Cationic compounds and their use as macro molecular carriers

2006-07-25

2006-07-25

Seidleok, James J. (Department: 1711)

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

C525S054110, C424S192100, C424S193100, C424S280100, C514S002600, C514S015800, C530S300000, C530S332000

Reexamination Certificate

active

07081495

ABSTRACT:
Dendrimers comprising a dentritic polypeptide with one dendron having terminal cationic groups and a lipidic anchor, preferably comprising C6-24-alkyl group containing α-amino acyl groups, preferably joined to the focal group, are used to assist transfection of cells in vitro and in vivo by DNA. The complex of dendrimer and DNA may be used in gene therapy, for instance to delivery clotting factor genes to cells.

REFERENCES:
patent: 6194543 (2001-02-01), Florence et al.
patent: 0884327 (1998-12-01), None
patent: 94/02506 (1994-02-01), None
patent: 98/40502 (1998-09-01), None
T. Sakthivel, et al., “Synthesis and Physiochemical Properties of Lipophilic Polyamide Dendrimers”,Chemical Abstracts, vol. 129, No. 6, Aug. 10, 1998, Abstract No. 68022.
A.V. Kabanov, et al., “DNA Complexes With Polycations For the Delivery of Genetic Material Into Cells”,Bioconjugate Chemistry, vol. 6, No. 1, Jan. 1, 1995, pp. 7-20.

Affiliated with

Also associated with

Rating

Cationic compounds and their use as macro molecular carriers does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cationic compounds and their use as macro molecular carriers, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cationic compounds and their use as macro molecular carriers will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3566992