Organic compounds -- part of the class 532-570 series – Organic compounds – Radioactive metal containing
Patent
1988-10-06
1990-04-10
Lechert, Jr., Stephen J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Radioactive metal containing
424 11, A61K 4300, A61K 4900, C07B 5900, C07F 1300
Patent
active
049162144
ABSTRACT:
The invention concerns cationic complexes of Technetium-99m with bidentate ligands (L), including complexes having the formulae [Tc(NO) X L.sub.2 ].sup.+ and [Tc L.sub.3 ].sup.+, which are of interest as heart imaging agents. The ligands are characterized by having the formula Y.sub.2 QZQY.sub.2, where each Q is phosphorus or arsenic, Z is a 2 or 3 carbon atom linking group, and at least one of the groups Y and Z includes at least one --COC--ether group.
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Chiu Kwok W.
Edwards Peter G.
Griffiths David V.
Kelly James D.
Latham Ian A.
Amersham International plc.
Caress Virginia B.
Lechert Jr. Stephen J.
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