Cationic amphiphiles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...

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514 75, 554 78, 554 79, 554 80, 424450, 424812, A61K31/685

Patent

active

059028025

ABSTRACT:
Cationic amphiphiles are provided that are alkyl or alkoxyalkyl O-phosphate esters of diacylphosphatidyl zwitterionic compounds such as phosphatidylcholine or phosphatidyl ethanolamine. The amphiphiles can be used as carriers for delivering macromolecules intracellularly.

REFERENCES:
Felgner et al., Chem. abstr of "Cationic Liposomes mediated transfection.", 1989.

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