Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1996-07-15
1999-08-17
Campell, Bruce R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514 2, 424450, 552544, A61K 9127, A61K 4800, A61K 3800, C07J 900
Patent
active
059394013
ABSTRACT:
Novel cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. By this invention, such cationic amphiphile is used in a state in which it is capable of accepting additional protons, i.e., it is not fully protonated. For purposes of this invention, cationic amphiphiles may be considered to encompass four general categories: (A) T-shaped/steroid-based amphiphiles; (B) T-shaped
on steroid-based amphiphiles; (C) non T-shaped/steroid based amphiphiles and (D) non T-shaped
on steroid-based amphiphiles.
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Chang Chau-Dung
Cheng Seng H.
Eastman Simon J.
Harris David J.
Lee Edward R.
Campell Bruce R.
Genzyme Corporation
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