Cation-exchange displacement chromatography process and...

Details Cation-exchange displacement chromatography process and... Cation-exchange displacement chromatography process and...

2006-10-23

2009-12-15

Therkorn, Ernest G (Department: 1797)

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

C210S656000, C210S659000, C210S198200, C530S413000, C530S416000, C530S417000

Reexamination Certificate

active

07632409

ABSTRACT:
A displacement chromatography process and displacer compounds used in the process and having the general formula (I):wherein:each group R1, R2, R3, R′1, R′2, and R′3, independently may be selected from alkyl, aryl, and aralkyl, and in which a ring containing one or more quaternary nitrogen may be formed by any one or more of R1and R2, R1and R′1, R1and R4, R4and R′4, or R4and R5;each R4, R′4, R5and R′5independently may be selected from alkyl, aryl, aralkyl and —(CH2)a—(CHY)b—(CH2)c—N+R1R2R3An−, wherein R1, R2and R3are as defined above;each Y independently may be selected from —H, —OH, —OR6, halo, alkyl, aryl and aralkyl, wherein —R6may be alkyl or —(CH2)a—(CHOH)b—(CH2)c—N+R1R2R3An−, wherein R1, R2and R3are as defined above;each q and z independently may be any whole number from 0 to about 6, with the proviso that q+z is equal to or less than about 6;each a, b, and c independently may be any whole number from 0 to 2, with the proviso that the sum a+b+c in any fragment is at least 1; andeach An−independently may be one or more organic or inorganic, monovalent or polyvalent anion as needed to obtain a neutral compound.

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