Catheter device and method of use for intramural delivery of pro

Details Catheter device and method of use for intramural delivery of pro Catheter device and method of use for intramural delivery of pro

1992-01-02

1993-09-07

Rosenbaum, C. Fred

Surgery

Means for introducing or removing material from body for...

Treating material introduced into or removed from body...

604101, A61M 2900

Patent

active

052423972

ABSTRACT:
The present invention discloses a method of treatment of an atherosclerotic blood vessel. Protein kinase C and tyrosine protein kinase inhibitors are delivered by means of a specialized catheter system to the deeper layers of the vessel wall with only minimal interruption of the vessel endothelium. This system will allow high local concentrations of otherwise toxic agents directly at the site of an atherosclerotic plaque to prevent and/or reduce the incidence of late restenosis attributed to cellular hyperplasia or rethrombosis.

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