Surgery – Radioactive substance applied to body for therapy – Radioactive substance placed within body
Patent
1997-11-04
1998-12-22
Lacyk, John P.
Surgery
Radioactive substance applied to body for therapy
Radioactive substance placed within body
A61M 2510, A61N 500
Patent
active
058511717
ABSTRACT:
The invention is directed to a catheter assembly with blood perfusion capability suitable for maintaining patency of a body lumen for a period of time sufficient to allow delivery of a radiation source to the body lumen. The catheter assembly includes an inner tubular member which extends coaxially within an outer tubular member, with the distal ends of the inner and outer tubular members being joined together. The catheter includes an expandable region which maintains and centers a radiation source within the body lumen while not inhibiting blood to perfuse around and past the expandable region. In one embodiment, the expandable region includes a plurality of outwardly extendable strap-like members which are formed on the outer tubular member of the elongated catheter body. A plurality of the strap-like members can be spaced in a staggered arrangement along the outer tubular member so that when moved to an expanded position, the strap-like members center the radiation source wire within the body lumen.
REFERENCES:
patent: 4697575 (1987-10-01), Horowitz
patent: 4706652 (1987-11-01), Horowitz
patent: 4748982 (1988-06-01), Horzewski et al.
patent: 4762130 (1988-08-01), Fogarty et al.
patent: 4763671 (1988-08-01), Goffinet
patent: 4771778 (1988-09-01), Mar
patent: 4775371 (1988-10-01), Mueller, Jr.
patent: 4815449 (1989-03-01), Horowitz
patent: 4861520 (1989-08-01), van't Hooft et al.
patent: 4940064 (1990-07-01), Desai
patent: 4969863 (1990-11-01), van't Hooft et al.
patent: 4976720 (1990-12-01), Machold et al.
patent: 4983167 (1991-01-01), Sahota
patent: 4998917 (1991-03-01), Gaiser et al.
patent: 5002560 (1991-03-01), Machold et al.
patent: 5015230 (1991-05-01), Martin et al.
patent: 5032113 (1991-07-01), Burns
patent: 5034001 (1991-07-01), Garrison et al.
patent: 5059166 (1991-10-01), Fischell et al.
patent: 5061273 (1991-10-01), Yock
patent: 5084002 (1992-01-01), Liprie
patent: 5176661 (1993-01-01), Evard et al.
patent: 5180368 (1993-01-01), Garrison
patent: 5199939 (1993-04-01), Dake et al.
patent: 5213561 (1993-05-01), Weinstein et al.
patent: 5242396 (1993-09-01), Evard
patent: 5258419 (1993-11-01), Rolando et al.
patent: 5263963 (1993-11-01), Garrison
patent: 5267960 (1993-12-01), Hayman et al.
patent: 5273738 (1993-12-01), Matthews et al.
patent: 5295959 (1994-03-01), Gurbel et al.
patent: 5295960 (1994-03-01), Aliahmad et al.
patent: 5295995 (1994-03-01), Kleiman
patent: 5302168 (1994-04-01), Hess
patent: 5306246 (1994-04-01), Sahatjian et al.
patent: 5308356 (1994-05-01), Blackshear, Jr. et al.
patent: 5350361 (1994-09-01), Tsukashima et al.
patent: 5352199 (1994-10-01), Tower
patent: 5354257 (1994-10-01), Roubin et al.
patent: 5395333 (1995-03-01), Brill
patent: 5411466 (1995-05-01), Hess
patent: 5456667 (1995-10-01), Ham et al.
patent: 5458572 (1995-10-01), Campbell et al.
patent: 5484384 (1996-01-01), Fearnot
patent: 5503613 (1996-04-01), Weinberger
patent: 5503614 (1996-04-01), Liprie
patent: 5507301 (1996-04-01), Wasicek et al.
patent: 5540659 (1996-07-01), Teirstein
patent: 5643171 (1997-07-01), Bradshaw et al.
patent: 5730698 (1998-03-01), Fischell et al.
Lindsay, et al., Aortic Arteriosclerosis in the Dog After Localized Aortic X-Irradiation, Circulation Research, vol. X, Jan. 1962.
Friedman, et al.,The Antiatherogenic Effect of Iridium.sup.192 Upon the Coloesterol-Fed Rabbit, Journal of Clinical Investigation, 1964.
Friedman, et al., Effect of Iridium.sup.192 Radiation on Thromboatherosclerotic Plaque in the Rabbit Aorta, Arch Path, vol. 80, Sep. 1965.
Hoopes, et al., Intraoperative Irradiation of the Canine Abdominal Aorta and Vena Cava, Int'l Journal of Radiation Oncology, Biology, Physics, vol. 13, No. 5, May 1987.
Weshler, et al., Inhibition by Irradiation of Smooth Muscle Cell Proliferation in the De-Endothelialized Rat Aorta, 21st Meeting -European Society for Radiation Biology, collected in Frontiers of Radiation Biology, 1988.
Dawson, John T., Theoretic Considerations Regarding Low-Dose Radiation Therapy for Prevention of Restenosis After Angioplasty, Texas Heart Institute Journal, vol. 18, No. 1, 1991.
Johnson, M.D., et al., Review of Radiation Safety in the Cardiac Catheterization Laboratory, Catheterization and Cardiovascular Diagnosis, 1992.
Schwartz, M.D., et al., Effect of External Beam Irradiation on Neointimal Hyperplasia After Experimental Coronary Artery Injury, Journal of the American College of Cardiology, vol. 19, No. 5, Apr. 1992.
March, M.D., et al., 8-Methoxypsoralen and Longwave Ultraviolet Irradiation Are a Novel Antiproliferative Combination for Vascular Smooth Muscle, Krannert Institute of Cardiology, Sep. 1992.
Hunink, M.D., et al., Risks and Benefits of Femoropopliteal Percutaneous Balloon Angioplasty, Journal of Vascular Surgery, vol. 17, No. 1, Jan. 1993.
Weintraub, M.D., et al., Can Restenosis After Coronary Angioplasty be Predicted From Clinical Variables?, Journal of the American College of Cardiology, vol. 21, No. 1, Jan. 1993.
Kuntz, M.D., et al., Generalized Model of Restenosis After Conventional Balloon Angioplasty, Stenting and Directional Atherectomy, Journal of the American College of Cardiology, vol. 21, No. 1, Jan. 1993.
Haude, M.D., Quantitative Analysis of Elastic Recoil After Balloon Angioplasty and After Intracoronary Implantation of Balloon-Expandable Palmaz-Schatz Stents, Journal of the American College of Cardiology, vol. 21, No. 1, Jan. 1993.
Schwartz, et al., Differential Neointimal Response to Coronary Artery Injury in Pigs and Dogs, Implications for Restenosis Models, Arteriosclerosis and Thrombosis, vol. 14, No. 3, Mar. 1994.
Liermann, et al., Prophylactic Endovascular Radiotherapy to Prevent Intimal Hyperplasia After Stent Implantation in Femoropopliteal Arteries, CardioVascular and Interventional Radiology, (1994).
Wiedermann, et al., Effects of High-Dose Intracoronary Irradiation on Vasomotor Function and Smooth Muscle Histopathology, Intracoronary Irradiation and Vasomotion, Jan. 1994.
Wagner, et al., Potential Biological Effects Following High X-Ray Dose Interventional Procedures, Journal of Vascular and Interventional Radiology, Jan.-Feb. 1994, pp. 71-84.
Wiedermann, M.D., et al., Intracoronary Irradiation Markedly Reduces Restenosis After Balloon Angioplasty in a Porcine Model, Journal of the American College of Cardiology, vol. 23, No. 6, May 1994.
Kakuta, M.D., et al., Differences in Compensatory Vessel Enlargement, No Intimal Formation, Account for Restenosis After Angioplasty in the Hypercholesterolemic Rabbit Model, Circulation Research, vol. 89, No. 6, Jun. 1994.
Fischell, M.D., et al., Low-Dose, .beta.-Particle Emission from `Stent` Wire Results in Complete, Localized Inhibition of Smooth Muscle Cell Proliferation, Circulation Research, vol. 90, No. 6, Dec. 1994.
Waksman, M.D., et al., Endovascular Low-Dose Irradiation Inhibits Neointima Formation After Coronary Artery Balloon Injury in Swine: A Possible Role for Radiation Therapy in Restenosis Prevention, Circulation Research, vol. 91, No. 5, Mar. 1, 1995.
Wiederman, M.D., Intracoronary Irradiation Markedly Reduces Neointimal Proliferation After Balloon Angioplasty in Swine: Persistent Benefit at 6-Month Follow-Up, Journal of the American College of Cardiology, vol. 25, No. 6, May 1995.
Waksman, M.D., et al., Intracoronary Radiation Before Stent Implantation Inhibits Neointima Formation in Stented Porcine Coronary Arteries, Circulation Research, vol. 92, No. 6, Sep. 15, 1995.
Verin, M.D., et al., Intra-Arterial Beta Irradiation Prevents Neointimal Hyperplasia in a Hypercholesterolemic Rabbit Restenosis Model, Circulation Research, vol. 92, No. 8, Oct. 15, 1995.
Waksman, M.D., et al., Intracoronary Low-Dose .beta.-Irradiation Inhibits Neointima Formation After Coronary Artery Balloon Injury in the Swine Restenosis Model, Circulation Research, vol. 92, No. 10, Nov. 15, 1995.
Hehrlein, C., et al., Radioactive Stents, Discoveries in Radiation for Restenosis, Abstract 22 (Jan. 1996).
Fischell, Tim A., M.D., A Beta-Particle Emitting Radioisotope Stent for the Prevention of Restenosis, Discoveries in Radiation for Restenosis, Abstract 23 (Jan. 1
Advanced Cardiovascular Systems Inc.
Gilbert Samuel
Lacyk John P.
LandOfFree
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