Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Hydrolase
Patent
1997-05-07
1999-01-19
Grimes, Eric
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Hydrolase
4353201, 435325, 536 232, 536 235, 536 2431, C12N 1511, C12N 1557, C12N 1563, C12P 2102
Patent
active
058612980
ABSTRACT:
The invention relates to cathepsin K polypeptides, polynucleotides encoding the polypeptides, methods for producing the polypeptides, in particular by expressing the polynucleotides, and agonists and antagonists of the polypeptides. The invention further relates to methods for utilizing such polynucleotides, polypeptides, agonists and antagonists for applications, which relate, in part, to research, diagnostic and clinical arts.
REFERENCES:
patent: 5501969 (1996-03-01), Hastings et al.
Inaoka et al., Biochem. Biophys. Res. Comm. 206:89-96, Jan. 1995.
Bromme et al., Biol. Chem. Hoppe-Seyler 376:379-384, Jun. 1995.
Adams Mark D.
Blake Judith A.
Debouck Christine M.
Drake Fred H.
Fitzgerald Lisa M.
Grimes Eric
Han William T.
Human Genome SciencesInc
King William T.
SmithKline Beecham Corporation
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