Cathepsin G-inhibiting aptamers

Details Cathepsin G-inhibiting aptamers Cathepsin G-inhibiting aptamers

1996-11-19

1998-07-14

Kight, John

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

536 245, 435 6, A61K 3170, C07H 2104

Patent

active

057804494

ABSTRACT:
Cathepsin G-inhibiting aptamers comprising oligonucleotides selected from the group consisting of the consensus sequences: ##STR1## wherein N represents nucleotides and the figures represent the number of possible nucleotides at that site; said cathepsin G-inhibiting aptamers are suggested as medicament.

REFERENCES:
patent: 5217951 (1993-06-01), Lezdey et al.
patent: 5290762 (1994-03-01), Lezdey et al.
patent: 5510333 (1996-04-01), Angelastro et al.
patent: 5514694 (1996-05-01), Powers et al.
patent: 5612194 (1997-03-01), Rubin et al.
Krieg et al., "CpG Motifs in Bacterial DNA Trigger Direct B-Cell Activation," Nature, 374, 546-549 (6 Apr. 1995).

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