Cathepsin cysteine protease inhibitors

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S398000, C546S192000, C546S330000, C548S335100

Reexamination Certificate

active

07405229

ABSTRACT:
This invention relates to a class of compounds having the general formula (I) which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.

REFERENCES:
patent: 6313117 (2001-11-01), Bekkali et al.
patent: WO 01/96285 (2001-12-01), None
patent: WO 02/069901 (2002-09-01), None
patent: WO 03/041649 (2003-05-01), None
Obach R.S., Drug-drug interactions; An important negative attribute in Drugs. Drugs of Today, 39(5), 301-38, 2003.

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