Catecholamine regulated protein

Details Catecholamine regulated protein Catecholamine regulated protein

2011-03-08

2011-03-08

Chernyshev, Olga N (Department: 1649)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C435S069100, C435S006120, C435S007100, C435S007920, C536S023100, C536S023500

Reexamination Certificate

active

07902336

ABSTRACT:
A novel family of mammalian catecholamine proteins is identified. These proteins are useful in methods of diagnosing neurological diseases, including schizophrenia and bipolar disease, as well as cardiovascular disease. This family of CRP40 proteins are also useful to treat neurological diseases.

REFERENCES:
patent: 5627039 (1997-05-01), Pereira-Smith et al.
patent: 7078375 (2006-07-01), Larsen et al.
Domanico et al., 1993, Mol. And Cell. Biology, pp. 3598-3610.
Benes, “Emerging Principles of Altered Neural Circuitry in Schizophrenia”, Brain Research Reviews, vol. 31, No. 2-3, Mar. 13, 2000, pp. 251-269.
Ben-Zvi, et al., “Review: Mechanisms of Disaggregation and Refolding of Stable Protein Aggregates by Molecular Chaperones”, Journal of Structural Biology, vol. 135, No. 2, Jul. 25, 2001, pp. 84-93.
Bradford, “A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding”, Analytical Biochemistry, vol. 72, Jan. 29, 1976, pp. 248-254.
Crowe, et al., “Report of the Chromosome 5 Workshop of the Sixth World Congress on Psychiatric Genetics”, American Journal of Medical Genetics (Neuropsychiatric Genetics) vol. 88, No. 3, May 10, 1999, pp. 229-232.
Gabriele et al., “Asymmetric Modulation of a Catecholamine-regulated Protein in the Rat Brain, Following Quinpirole Administration”, Synapse, vol. 49, No. 4, Jun. 20, 2003, pp. 261-269.
Gabriele et al., “Modulation of a 40-kDa Catecholamine-regulated Protein Following D-amphetamine Treatment in Discrete Brain Regions”, European Journal of Pharmacology, vol. 453, No. 1, Oct. 18, 2002, p. 13-19.
Gabriele et al., “Decreased Expression of a 40-kDa Catecholamine-regulated Protein in the Ventral Striatum of Schizophrenic Brain Specimens From the Stanley Foundation Neuropathology Consortium”, Schizophrenia Research, vol. 74, No. 1, Apr. 1, 2005, pp. 111-119.
Giffard et al., “Chaperones, Protein Aggregation, and Brain Protection From Hypoxic/ischemic Injury”, The Journal of Experimental Biology 207, Aug. 6, 2004, pp. 3213-3220.
Goto et al., “Immunohistochemical Localization of a 40-kDa Catecholamine Regulated Protein in the Nigrostriatal Pathway”, Brain Research, vol. 900, No. 2, May 11, 2001, pp. 314-319.
Graveley, “Alternative Splicing: Increasing Diversity in the Proteomic World”, Trends in Genetics, vol. 17, No. 2, Feb. 2001, pp. 100-107.
Grover, “Molecular Biology of Stress Responses”, Cell Stress & Chaperones, vol. 7, No. 1, Jan. 2002, pp. 1-5.
Hong et al., “Genetic Mapping Using Haplotype and Model-Free Linkage Analysis Supports Previous Evidence for a Locus Predisposing to Severe Bipolar Disorder at 5q31-33”, American Journal of Medical Genetics Part B (Neuropsychiatric Genetics) 125B, Feb. 2004, pp. 83-86.
Kaul et al., “Mortalin: Present and Prospective”, Experimental Gerontology, vol. 37, No. 10-11, Oct.-Nov. 2002, pp. 1157-1164.
Kaul et al., “Overexpressed Mortalin (mot-2)/mthsp70/GRP75 and hTERT Cooperate to Extend the in vitro Lifespan of Human Fibroblasts”, Experimental Cell Research, vol. 286, No. 1, May 15, 2003, pp. 96-101.
Knable, “Schizophrenia and Bipolar Disorder: Findings From Studies of the Stanley Foundation Brain Collection”, Schizophrenia Research, vol. 39, No. 2, Jun. 3,1999, pp. 149-152.
Knable et al., “Multivariate Analysis of Prefrontal Cortical Data from the Stanley Foundation Neuropathology Consortium”, Brain Research Bulletin, vol. 55, No. 5, Jul. 15, 2001, pp. 651-659.
Lewis et al., “Genome Scan Meta-analysis of Schizophrenia and Bipolar Disorder Part II:Schizophrenia”, American Journal Human Genetics 73, Jul. 2003, pp. 34-48.
Macario et al., “Sick Chaperones and Ageing: A Perspective”, Ageing Research Reviews 1, Apr. 2002, pp. 295-311.
Matsumoto et al., “Catechol O-methyltransferase (COMT) mRNA Expression in the Dorsolateral Prefontal Cortex of Patients with Schizophrenia”, Neuropsychopharmacology 28, Apr. 23, 2003, pp. 1521-1530.
Modi et al., “Modulation of Brain Catecholamine Absorbing Proteins by Dopaminergic Agents”, European Journal Pharmacology 299, Mar. 1996, pp. 213-220.
Modrek et al., “Alternative Splicing in the Human, Mouse, and Rat Genomes is Associated with an Increased Frequency of Exon Creation and/or Loss”, Nature Genetics, vol. 34, No. 2, Jun. 2003, pp. 177-180.
Muchowski et al., “Modulation of Neurodegeneration by Molecular Chaperones”, Nature Reviews, Neuroscience, vol. 6, Jan. 2005, pp. 11-22.
Nair et al., “Molecular Cloning, Localization and Characterization of a 40-kDa Catecholamine-regulated Protein”, Journal Neurochemistry 76, Oct. 19, 2001, pp. 1142-1152.
Ohtsuka et al., “Roles of Molecular Chaperones in the Nervous System”, Brain Research Bulletin, vol. 53, No. 2, Jun. 15, 2000, pp. 141-146.
Perlman et al., “Postmortem Investigations of the Pathophysiology of Schizophrenia: The Role of Susceptibility Genes”, Journal Psychiatry Neuroscience, vol. 29, No. 4, Feb. 17, 2004, pp. 287-293.
Pira et al., “The Atypical Antipsychotic Quetiapine Increases Both Noradrenaline and Dopamine Release in the Rat Prefrontal Cortex”, European Journal of Pharmacology 504, Sep. 21, 2004, pp. 61-64.
Ross et al., “Covalent Affinity Labeling of Brain Catecholamine-absorbing Proteins Using a High-specific-activity Substituted Tetrahydronaphthalene”, Journal of Neurochemistry 65, Jun. 29, 1995, pp. 2783-2789.
Ross et al., “Identification of Novel Catecholamine Absorbing Proteins in the Central Nervous System”, Journal of Molecular Neuroscience, vol. 4, Sep. 1993, pp. 141-148.
Seamans et al., “The principal features and mechanisms of dopamine modulation in the prefrontal cortex”, Progress in Neurobiology 74, May 4, 2004, pp. 1-57.
Seeman et al., “Schizophrenia: more dopamine, more D2 receptors”, Proc Natl Acad Sci, vol. 97, No. 14, Jul. 5, 2000, pp. 7673-7675.
Selemon et al., “Cellular pathology in the dorsolateral prefrontal cortex distinguishes schizophrenia from bipolar disorder”. Current Molecular Medicine, vol. 3, No. 5, Aug. 2003, 427-436.
Sharan, et al., “Cocaine treatment increases expression of a 40 kDa catecholamine-regulated protein in discrete brain regions”, Synapse, vol. 47, No. 1, Oct. 30, 2002, pp. 33-44.
Sharan et al., “Modulation of a 40-kDa catecholamine regulated protein by dopamine receptor antagonists”, European Journal of Pharmacology, vol. 413, No. 1, Feb. 9, 2001, pp. 73-79.
Sherman et al., “Cellular defenses against unfolded proteins: a cell biologist thinks about neurodegenerative diseases”, Neuron, vol. 29, Jan. 2001, pp. 15-32.
Sklar et al., “Genome-wide scan in Portuguese Island families identifies 5q31-5q35 as a susceptibility locus for schizophrenia and psychosis”, Molecular Psychiatry, 9, Dec. 2003, 213-218.
Soti et al., “Chaperones and aging: role in neurodegeneration and in other civilizational diseases”, Neurochemistry International, 41, Jan. 7, 2002, pp. 383-389.
Soti et al., “Chaperones come of age”, Cell Stress & Chaperones, vol. 7, No. 2, Jan. 16, 2002, pp. 186-190.
Svensson, “Alpha-adrenoceptor modulation hypothesis of antipsychotic atypicality”, Progress in Neuro-psychopharmacoly & Biological Psychiatry, 27, Sep. 9, 2003, pp. 1145-1158.
Wadhwa et al., “Protein markers for cellular mortality and immortality”, Mutatation Research, 256, Jul. 1, 1991, pp. 243-254.
Wadhwa et al., “An Hsp70 family chaperone, mortalin/mthsp70/PBP74/Grp75: what, when, and where?”, Cell Stress & Chaperones, vol. 7, No. 3, Apr. 16, 2002, pp. 309-316.
Weinberger, “Schizophrenia and the frontal lobe”, Trends Neuroscience, vol. 11, No. 8, Aug. 1988,

Affiliated with

Also associated with

Rating

Catecholamine regulated protein does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Catecholamine regulated protein, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Catecholamine regulated protein will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2671774