Catalytic system and method for coupling of aromatic compounds

Organic compounds -- part of the class 532-570 series – Organic compounds – Heavy metal containing

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502170, 502171, 562480, 585427, 560 96, C07F 1500, C07C 6700, B01J 3100

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active

061039195

ABSTRACT:
A catalytic process for production of biphenyl and its derivatives by coupling of substituted or unsubstituted monoaryl compounds in the presence of a catalytic system comprising at least one Pd (II) compound and a strong acid or a mixture of acids. The process provides high conversions and high selectivity under mild temperature conditions and short reaction times. The strong acid or mixture of acids has a Hammett acidity of less than about -10, and contains a predominant amount of counterions which form a weak ligand complex with palladium (II). The method is highly selective to formation of desired biaryl isomers, such as 4,4'-isomers, and allows control of the relative amounts of isomers of biaryl compounds and substituted monoaryl compounds in the final product.

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