Catalytic compositions and methods for asymmetric aldol...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C546S208000, C540S596000, C540S597000, C540S602000, C548S523000, C548S518000

Reexamination Certificate

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06919456

ABSTRACT:
Methods and compositions are provided for the direct catalytic asymmetric aldol reaction of aldehydes with donor molecules selected from ketones and nitroalkyl compounds. The reactions employ as catalyst a Group 2A or Group 2B metal complex of a ligand of formula I, as defined further herein.

REFERENCES:
Trost, J Am Chem Soc, 2000, vol 122, pp 12003-12004.
Trost, J Am Chem Soc, 2001, vol 123, pp 3367-3368.

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