Catalytic asymmetric and non-asymmetric reduction of times and o

Details Catalytic asymmetric and non-asymmetric reduction of times and o Catalytic asymmetric and non-asymmetric reduction of times and o

1991-11-14

1994-03-08

Higel, Floyd D.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548579, 549491, 564302, 564303, 564304, 564305, 564355, 564356, 564374, 564375, 564378, 564385, 564392, 564415, C07D20702, C07D30702, C07D20706, C07C20940, C07C20952

Patent

active

052928934

ABSTRACT:
A process is provided for catalytically reducing imines, oximes, hydrazones and related compounds. Moreover, there is provided a process for the catalytic asymmetric reduction of imines, oximes, hydrazones, and the like, using enantiomerically enriched catalysts, to provide chiral amine reaction products which are enriched in one enantiomer. Catalytic asymmetric reduction can also be carried out using an achiral precatalyst in combination with a

REFERENCES:
patent: 1845280 (1932-02-01), Jager
patent: 3412174 (1968-11-01), Kroll
patent: 3873621 (1975-03-01), Kreevoy et al.
patent: 3932534 (1976-01-01), Fukunaga et al.
patent: 4078002 (1978-03-01), Brown
patent: 4372893 (1983-02-01), Eckert
patent: 4532351 (1985-07-01), Barnett et al.
patent: 4985567 (1991-01-01), Achiwa et al.
Hajos, "Studies in Organic Chemistry 1, Complex Hydrides and Related Agents in Organic Synthesis", pp. 190 to 193 (1979).
Nicolaou et al, Angew. Chem. Int Ed. Eng, vol. 30, pp. 585-588 (1991).
Iridium (III) Hydride Complexes for the Catalytic Enantioselective Hydrogenation Of Imines, Chan et al. (J. Am. Chem. Soc., 1990, 112, 9400).
Enantioselektive Hydrosilylierung von prochiralen 3,4-Dihydro-2H-pyrrol-Derivaten Becker et al. (Angew. Chem., 1985, 93, 969).
Organocerium Additions to SAMP-Hydrazones: General Synthesis of Chiral Amines Denmark et al. (J. Am. Chem. Soc., 1987, 109, 2224).
Chiral Toluene-2,x-Sultam Auxiliaries: Preparation and Structure of Enantiomerically Pure (R)- and (S)-Ethyl-2,1'-Sultam.sup.1, Oppolzer et al. (Tetrahedron Lett., 1990, 31, 4117).
Asymmetric Hydrosilylation of a Schiff Base of Acetophenone Catalyzed by Rh(AMPP) Complexes, Kokel et al. (J. Mol. Cat., 1989, 57, L5-L7).
Asymmetric Homogeneous Hydrogenation of Imines Using Rhodium-Phosphine Systems, Cullen et al. (J. Mol. Cat., 1990; 62, 243).
Novel Diphosphinoiridium Catalysts for the Enantioselective Hydrogenation of N-Arylketimines, Spindler et al. (Angew. Chem. Int. Ed. Eng., 1990, 29, 558).
Rhodium(1)-catalysed Asymmetric Hydrogenation of Imines, Kang et al. (J. Organomet. Chem., 1975, 90, 353).
Reduction Asymetrique Catalysee Par Des Complexes De Metaux De Transition, Kagan et al. (J. Organomet. Chem., 1975, 90, 353).
Synthesis and Molecular Structures of Chiral Titanocene Derivatives with Bridged Tetrahydroindenyl Ligands, Wild et al. (J. Organomet. Chem., 1982, 232, 233).
Enantioselective hydrosilylation of ketones by diphenylsilane with RH (cod)Cl.sub.2 /pyridinethiazolidine Catalysts, Brunner et al. (J. Organomet. Chem., 1988, 346, 413).
Rhodium Phosphine Complexes as Homogeneous Catalysts. 14. Asymmetric Hydrogenation of a Schiff Base of Acetophenone-Effect of Phosphine and Catalyst Structure on Enantioselectivity, Vastag et al. (J. Mol. Cat. 1984, 22, 283).
Catalytic and structural studies of RH.sup.1 complexes of (-) (2S,4S)-2,4-bis (diphenylphosphino)pentane. Asymmetric hydrogenation of acetophenonebenzylimine and acetophenone, Bakos et al. (J. Organomet. Chem., 1989; 370, 263).
Diastereomeric Derivatisation and Enantiomer Separation of Ethylenebis (Tetrahydroindenyl)-Titanium and -Zirconium Dichlorides, Schafer et al. (J. Organomet. Chem., 1987, 328, 87).

Affiliated with

Also associated with

Rating

Catalytic asymmetric and non-asymmetric reduction of times and o does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Catalytic asymmetric and non-asymmetric reduction of times and o, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Catalytic asymmetric and non-asymmetric reduction of times and o will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-154774