CASH (Caspase Homologue) with death effector domain,...

Details CASH (Caspase Homologue) with death effector domain,... CASH (Caspase Homologue) with death effector domain,...

2006-06-08

2008-09-02

Spector, Lorraine (Department: 1647)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C536S023500, C435S320100, C435S325000, C435S007100, C435S071200

Reexamination Certificate

active

07419804

ABSTRACT:
Proteins capable of modulating or mediating the function of MORT-1 are disclosed. Also disclosed are DNA sequences encoding these proteins, the recombinant production of these proteins as well as their use.

REFERENCES:
patent: 6207458 (2001-03-01), Chaudhary et al.
patent: 6242569 (2001-06-01), Shu et al.
patent: 6623938 (2003-09-01), Ni et al.
patent: 2002/0052474 (2002-05-01), Shu et al.
patent: 2002/0095030 (2002-07-01), Tschopp et al.
patent: 2278349 (1998-03-01), None
patent: 2226973 (1998-05-01), None
patent: 0841399 (1998-05-01), None
patent: WO98/44104 (1998-03-01), None
Chinnaiyan et al, “The cell-death machine”,Cur Biol6(5):555-563 (1996).
Han et al., MRIT, a novel death-effector domain-containing protein, interacts with caspases and BcLXL and initiates cell death,Proc. Natl. Acad. Sci, 94:11333-11338 (1997).
Goltsev et al., CASH, a novel caspase homologue with death effector domains,J Biol Chem. 272:19641-19644 (1997).
XP-002071908—Takeda, Human pancreatic islet cDNA, Accession No. C055730,EMBL/GenBank/DDBJ databases, (1996).
XP-002071907—Hillier et al., Homo sapiens cDNA clone, Accession No. AA149562,EMBL/GenBank/DDBJ databases, (1996).
XP-002071906—Hillier et al., Soares senescent fibroblasts nBHSF Homo sapiens cDNA, Accession No. N94588,EMBL/GenBank/DDBJ databases, (1996).
Srinivasula et al., FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis,J Biol Chem., 272(30):18542-18545 (1997).
Phillips, The challenge of gene therapy and DNA delivery,J. Pharm Pharmacology, 53:1169-1174 (2001).
Bowie et al., Deciphering the Message in Protein Sequences: Tolerance to Amino Acid Substitutions,Science, 247:1306-1310 (1990).
Wells, Additivity of mutational effects in proteins,Biochemistry, 29:8509-8517 (1990).
Ngo et al., Computational complexity, protein structure prediction, and the levinthal paradox,in The Protein Folding Problem and Tertiary Structure Prediction, 491-495 (1994).
EM Phizicky et al., Microbiological Reviews, Protein-protein interactions: methods for detection and analysis, 59(1):94-123 (1995).

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