Cartilage intermediate layer protein 2 C1 and its use to...

Details Cartilage intermediate layer protein 2 C1 and its use to... Cartilage intermediate layer protein 2 C1 and its use to...

2007-03-27

2010-10-12

Ford, Vanessa L. (Department: 1645)

Chemistry: natural resins or derivatives; peptides or proteins;

Proteins, i.e., more than 100 amino acid residues

C424S520000, C424S549000, C530S324000, C530S388150

Reexamination Certificate

active

07812125

ABSTRACT:
A method for differentiation of osteoarthritis from rheumatoid arthritis and non-disease conditions in a sample, comprising measuring in the sample the concentration of human cartilage intermediate layer protein 2(CILP-2) in body fluids and more specifically, measuring in the sample the concentration of the N-terminal part of CILP-2 (2C1) or fragments thereof.

REFERENCES:
patent: 5876963 (1999-03-01), Mitchell et al.
patent: 6124095 (2000-09-01), Magna et al.
patent: 6251389 (2001-06-01), Magna et al.
Bowie et al (Science, 1990, 257:1306-1310).
Greenspan et al. (Nature Biotechnology 17: 936-937, 1999).

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