Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-05-22
2007-05-22
Romeo, David (Department: 1647)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S254110, C435S320100, C435S325000, C536S023500, C530S399000, C930S120000
Reexamination Certificate
active
10379830
ABSTRACT:
Nucleotide and amino acid sequences of cartilage-derived morphogenetic proteins (CDMP-1 and CDMP-2) from human and bovine cartilage extracts. These proteins exhibit chondrogenic activity and can be used to repair cartilage defects in a mammal.
REFERENCES:
patent: 4609551 (1986-09-01), Caplan et al.
patent: 4810691 (1989-03-01), Seyedin et al.
patent: 4935497 (1990-06-01), Veis et al.
patent: 5658882 (1997-08-01), Celeste et al.
patent: 5770444 (1998-06-01), Lee et al.
patent: 5801014 (1998-09-01), Lee et al.
patent: 5807713 (1998-09-01), Hötten et al.
patent: 5994094 (1999-11-01), Hötten et al.
patent: 6027919 (2000-02-01), Celeste et al.
patent: EP93/00350 (1993-08-01), None
patent: PCT/US94/00657 (1994-07-01), None
patent: PCT/US94/07762 (1995-01-01), None
patent: EP94/02630 (1995-02-01), None
Sambrook et al. Molecular Cloning: A Laboratory Manual. Second Edition, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, U.S.A. Nov. 1989, p. 9.47.
Spiro et al. Inductive activity of recombinant human growth and differentiation factor-5. Biochem Soc Trans. 2000;28(4):362-8.
Adamson, M.C., ET LA., “The mouse homolog of the Gibbon Ape Leukemia Virus Receptor: Genetic Mapping and a Possible Receptor Function in Rodents”, Virology 183, 778-781 (1991).
Alberts, et al., “Molecular Biology of the Cell”, Jan. 1994, Garland Publishing, Inc., New York, NY, p. 119.
Bowie, et al., Deciphering the message in protein sequences: tolerance to amino acid substitutions. Science, (Mar. 16, 1990), 247, (4948) pp. 1306-1310.
Chang, et al., “Cartilage-derived Morphogenetic Proteins”, Journal of Biology Chemistry, vol. 269, No. 45, Issue of Nov. 11, pp. 28227-28234 1994.
Chornczynski, P., et al., “Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate-Phenol-Chloroform Extraction”, Analytical Biochemistry 162, 156-159, (1987).
Grimaldi, J.C., et al., “Geonomic Structure and Chromosomal Mapping of the Murine CD40 Gene”, The Journal of Immunology 149, (12), 3921-3926, (1992).
Hötten, et al., Cloning and Expression of Recombinant Human Growth . . . , Biochemical and Biophysical Research Communications, vol. 204(2):646-52, Oct. 28, 1994.
Invitrogen Product Catalog, 1995, p. 31.
Kingsley, D.M. “The TGF-βsuperfamily: new members, new receptors, and new genetic tests of function in different organisms”, Genes and Development, (Jan. 1994) 8 (2) 133-146.
Luyten, F.P., et al., “Purification and Partial Amino Acid Sequence of Osteogenin, a Protein Initiating Bone Differentiation”, The Journal of Biological Chemistry 264 (23), 13377-13380, (1989).
Luyten, F.P., et al, “Recombinant Bone Morphogenetic Protein-4, Transforming Growth Factor β1, and Activin A enhance the Cartilage Phenotype of Articular Chonodrocytes in Vitro”, Experimental Cell Res. 210, 224-229 (1994).
Lyons, K. M., et al., “Organogenesis and Pattern Formation in the Mouse: RNA Distribution Patterns Suggest a Role for Bone Morphogenetic Protein-2a (BMP-2A)”, Development 109, 833-844 (1990).
Muthukumaran, N., et al., “Comparison of Bone Inductive Proteins of Rat an Porcine Bone Matrix”, Biochemical and Biophysical Research Communications 131 (1), 37-41, (1985).
Ngo, et al., “The Protein folding Problem and Tertiary Structure Prediction”, Merz and Le Grand (Eds), Aug. 1994, Springer Verlag, pp. 433-506 (Ch. 14).
Owens, E. M., et al., “Cell-Cell Interaction by Mouse Limb Cells During In Vitro Chondrogenesis, Analysis of the Brachpod Mutation1”, Developmental Biology 91, 376-388, (1982).
Paralkar, v. M. et al., “Affinity of Osteogenin, an Extracellular Bone Matrix Associated Protein Initiating Bone Differentiation, for Concanavalin A”, Biochemical and Biophysical Research Communications 160(2), 419-424, (1989).
Pelton, R.W., et al., “Expression of Transforming Growth Factor β2 RNA during Murine Embryogenesis”, Development 106, 759-767, (1989).
Ramachandran, G. N., et al., “Collagen and Cell Differentiation”, Biochemistry of Collagen, Ch. 9, pp. 449-478, (1976).
Reddi, A. H., “Bone morphogenetic proteins: an unconventional approach to isolation of first mammalian morphogens”, Cytokine and Growth Factor Reviews, 1997, vol. 8, No. 1, p. 11-20.
Sambrook, et al., “Molecular Cloning: A Laboratory Manual”, 2ndedition, vol. 1, 2, & 3, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, U.S.A., Nov. 1989, pp. 9.47-9.51, 11.4, 16.19 and 16.41-16.44.
Sampath, T.K., et al., “Isolation of Osteogenin, an extracellular matrix-associated, bone inductive protein, by Heparin Affinity Chomotography”, Proc. Natl. Acad. Sci. USA 84, 7109-7113 (1987).
Scheerlinck, J. Y., et al., “Rredistribution of a Murine Humoral Immune Response Following Removal of an Immunodominant B cell epitope from a recombinant Fusion Protein.” Molecular Immunology 30(8), 733-739 (1993).
Shah, et al., “Neutralisation of TGF-β1 and TGF-β2 or exogenous addition of TGF-β3 to cutaneous rat wounds reduces scanning”, Journal of Cell Science 108, 985-1002 (1995).
Siracusa, L. D., et al., “Mouse Chromosome 2”, Mammalian Genome 4:S31-S46, (1993).
Sorgenate, N., et al., “Extractability of Lysozyme from Bovine Nasal Cartilage”, Biochemica Biophysica Acta 284: 441-450, (1972).
Storm, E. E., et al., “Limb Alterations in Brachpodism Mice due to Mutations in a new Member of the TGF-β Superfamily”, Nature 368: 639-643 (1994).
Storm, et al., Genbank Accession No. U08338, National Institutes of Health, Bethesda, Maryland, U.S.A., Jun. 6, 1994.
Vukicevic, et al., “Developing Human Lung and Kidney are Major sites for Synthesis of Bone Morphogenetic Protein-3 (Osteogenin)”, The Journal of Hystochemistry and Cythochemistry 42(7): 869-875 (1994).
Vukicevic, et al., “Induction of nephrogenic mesenchyme by osteogenic protein 1 (bone morphogenetic protein 7)” Proc. Nat'l Acad Sci USA, Aug. 20, 1996; 93(17):9021-6.
Wozney, et al., “Novel Regulators of Bone Formation: Molecular Clones and Activities”, Science 242, 1528-1534, see Table 1 at p. 1531 (1988).
Chang Steven Chao-Huan
Luyten Frank P.
Moos, Jr. Malcolm
Knobbe Martens Olson & Bear LLP
Romeo David
The United States of America as represented by the Department of
LandOfFree
Cartilage-derived morphogenetic proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cartilage-derived morphogenetic proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cartilage-derived morphogenetic proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3794833