Cartilage and bone induction by artificially perforated organic

Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis – Bone

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623 66, A61F 238

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active

049329731

ABSTRACT:
A process of encouraging induction of cartilage and bone formation by organic bone matrix. The process involves forming a plurality of continous channel perforations in organic bone matrix prior to the implantation of same. These perforations become centers of cartilage and bone induction after the implantation of bone matrix and produce a significant increase in the ability of bone matrix to induce cartilage and bone formation.

REFERENCES:
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patent: 4553272 (1985-11-01), Mears
Holmes; "Bone Regeneration within a Cotallene Hydroxapatite Implant" Plastic & Reconstructure Surgery, vol. 63, No. 5, May 1979.
"Application of the Biological Principal of Induced Osteogenesis for Craniofacial Defects", by Julie Glowacki et al., The Lancet, May 2, 1981.
"Demineralized Bone Implants", by Julie Glowacki et al., Clinics in Plastic Surgery, vol. 12, No. 2, Apr. 1985.
"Use of Demineralized Allogenic Bone Implants for the Correction of Maxillocraniofacial Deformities", by John B. Mulliken, M. D.
"Chemosterilized Antigen-Extracted Surface-Demineralized Autolysed Allogenic (AAA) Bone for Arthrodesis", by Marshall R. Urist.

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