Carrier system against GNRH

Details Carrier system against GNRH Carrier system against GNRH

1995-05-30

1997-11-04

Sidberry, Hazel F.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 231, 536 237, 536 221, 4241801, 4241851, 4241931, 42419511, 4241981, 4242411, 4242421, 435 691, 435 694, 435 711, 4353201, 43525233, C07H 2104, C12N 1509, C12P 2106, A61K 39108

Patent

active

056841450

ABSTRACT:
The present invention is concerned with vaccination of mammals against GnRH. The vaccine comprises a GnRH peptide conjugate to E. coli fimbrial-filaments and elicits an immune response against GnRH.

REFERENCES:
Thiry et al Appl Environ Microbiol 55:984-993 1984.
Van Die et al Journal of Bacteriology 170:5870-5876 1988.
Van Die et al Mol. Gen Genet 222:297-303, 1990.
I. van Die et al., "Genetic Manipulation of Major P-Fimbrial Subunits and Consequences for Formation of Fimbriae," Journal of Bacteriology, 170:12:5870-5876, Dec. 1988.
C.A. Morrison et al., "Adjuvant-free Immunological Manipulation of Livestock," Research in Veterinary Science 37:108-113, 1984.
N. Sherwood et al.,"Characterization of Teleost Gonadtropin-Releasing Hormone" Neurobiology, 80:2794-2798, 1983.
R.P. Miller et al., "Receptor and Gonadtropin-Releasing Activity of a Novel !GnRH) and a D-Arg.sup.6 Analog," Endocrinology 119:1:224-231.
I. van Die et al., "Expression of Foreign Epitopes in P-Fimbriae of Escherichia Coli," Mol Gen Genet, (1990) 222:297-303.

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