Carrier proteins for vaccines

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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Reexamination Certificate

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07972608

ABSTRACT:
The present invention provides, among other things, improved carrier proteins for antigen-based vaccines, including polysaccharide-based vaccines. An aspect of the invention advantageously employs tetanus toxin Fragment C.

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patent: 6602508 (2003-08-01), Michon et al.
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Wessels et al. (Infection and Immunity, vol. 66, no. 5, pp. 2186-2192, May 1998).
Wessels et al. (Journal of Clinical Investigation, vol. 86, pp. 1428-1433 Nov. 1990).
Michon et al. (in Streptococci and Host. (Ed). Horaud et al. Plenum Press, New York, pp. 847-850, 1997).
Database Biosis Online, XP-002302424, Oct. 14, 2003; Kim et al., “Tetanus Toxin C-Fragment as a Universal Carrier Protein for Conjugate Vaccines”Abstracts of the Interscience Conference on Antimicrobial Agents and Chemotherapy,vol. 43, p. 294, Sep. 14-17, 2003.
International Search Report for PCT/US2004/020026, dated Nov. 15, 2004.

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