Chemistry: molecular biology and microbiology – Process of mutation – cell fusion – or genetic modification – Introduction of a polynucleotide molecule into or...
Reexamination Certificate
2006-10-17
2011-10-04
Whiteman, Brian (Department: 1635)
Chemistry: molecular biology and microbiology
Process of mutation, cell fusion, or genetic modification
Introduction of a polynucleotide molecule into or...
C424S450000, C514S04400A
Reexamination Certificate
active
08030075
ABSTRACT:
An object of the present invention is to provide a nucleic acid delivery carrier composition of low toxicity and high safety, the carrier composition, when used to administer a nucleic acid such as an siRNA into an animal-derived cell or organism, being capable of delivering efficiently the nucleic acids into the cells while protecting it from being degraded; and a nucleic acid deliver composition containing the carrier and a nucleic acid. The carrier composition for delivery of a nucleic acid is prepared by mixing (A) a cationic lipid having a steroid skeleton with (B) a tertiary ammonium salt-type cationic lipid. The nucleic acid delivery composition is prepared by mixing the nucleic acid delivery carrier with a nucleic acid.
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Office Action mailed Aug. 10, 2011, in corresponding Philippines Patent Application No. 12008500782 (in the name of Otsuka Pharmaceutical Co., Ltd.).
Miyao Hideo
Sato Masako
Sekiguchi Kazuo
Toyobuku Hidekazu
Otsuka Pharmaceutical Co. Ltd.
Sughrue & Mion, PLLC
Whiteman Brian
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