Carrier bound immunosorbent

Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

436524, 436527, 436532, 435 7, G01N 3354, G01N 3356

Patent

active

044789467

ABSTRACT:
The invention provides an immuno-reactant, being either an antigen or an antibody covalently bonded to a cross-linked film, more particularly composed of cross-linked protein or peptides, enveloping a carrier body, e.g. a solid, non-porous glass bead of 6 mm diameter. The immuno-logically active parts of the immuno-reactant are present on the surface in a form in which they are available for immunosorption. If the immuno-reactant is a protein, e.g. an antibody, it can provide all or part of the film-forming material. In a particular embodiment the film carries antibodies against a second type of antibody which is captured immunosorptively to form a "double layer" carrier-bound immunosorbent, the antigen capturing sites of the second type of antibody providing the immunosorption sites of the product. The immunosorbents are used, for example, for RIA or ELISA assays.

REFERENCES:
patent: 3646346 (1972-02-01), Catt
patent: 3790663 (1974-02-01), Garrison
patent: 3985617 (1976-10-01), Yugari et al.
patent: 4043869 (1977-08-01), Barker et al.
patent: 4123396 (1978-10-01), Rembaum et al.
patent: 4170685 (1979-10-01), Rembaum et al.
patent: 4197220 (1980-04-01), Rembaum
patent: 4267234 (1981-05-01), Rembaum
patent: 4280816 (1981-07-01), Elahi
patent: 4338094 (1982-07-01), Elahi
patent: 4369226 (1983-01-01), Rembaum
Hodes, M. E. et al., J. Chromatography, vol. 104, pp. 379-387, (1975).
Rembaum, A., Pure and Applied Chemistry, vol. 52, pp. 1275-1278, (1980).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Carrier bound immunosorbent does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Carrier bound immunosorbent, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carrier bound immunosorbent will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1599932

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.