Carotenoid ketolases

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

Reexamination Certificate

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C435S189000, C435S320100, C435S148000, C435S410000, C435S254300, C435S255200, C435S255500, C536S023200

Reexamination Certificate

active

11015433

ABSTRACT:
Novel CrtW carotenoid ketolase are provided that are useful for the production of ketocarotenoids. The ketolases genes of the present invention exhibit low homology in comparison to other CrtW ketolases previously reported. Expression of the carotenoid ketolases in heterologous hosts enabled production of canthaxanthin and astaxanthin. Coexpression experiments using divergent crtW genes resulted in increased production of the desired ketocarotenoids.

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patent: WO 02/079395 (2002-10-01), None
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