Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing compound containing a carotene nucleus
Reexamination Certificate
2006-07-11
2006-07-11
Patterson, Jr., Charles L. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing compound containing a carotene nucleus
C435S193000
Reexamination Certificate
active
07074588
ABSTRACT:
A ketolase gene has been isolated fromRhodococcus erythropolisAN12 strain encoding a carotenoid modification enzyme of the carotenoid biosynthetic pathway. The gene and gene product are the first isolated from aRhodococcusstrain. Six conserved amino acid motifs have been identified as the characteristic of this type of ketolase enzymes. The gene and gene product of the present invention may be used in a variety of ways for the production of keto-carotenoid compounds in a variety of organisms.
REFERENCES:
patent: 5750865 (1998-05-01), Bird et al.
patent: WO 02/18617 (2002-03-01), None
Hannibal et al., Isolation and Characterization of Canthaxanthin Biosynthesis Genes from the Photosynthetic Bacterium Brandyrhizobium sp. Strain ORS278, J. Bacteriol.(2000) 182: 3850-3853.
Fernandez-Gonzalez et al., A New Type of Asymmetrically Acting β-Carotene Ketolase Is Required for the Synthesis of Echinenone in the Cyanobacterium Synechocystis sp. PCC 6803, J.of Biol. Chem.(1997) 272;9728-9733.
Mann et al., Metabolic engineering of astaxanthin production in tobacco flowers, (2000) Nature Biotechnology, 18:888-892.
Ichiyama et al., Carotenoid Pigments of Genus Rhodococcus, Microbiol. Immunol. (1989), 33:503-508.
White O et al., Genome Sequence of the Radioresistant Bacterium Deinococcus radiodurans R1, Science 286 (5444), 1571-1577 (1999).
NCBI, Accession No. NC00091, Synechocystis CrtO(slr0088), Oct. 23, 2001.
NCBI, Accession No. AE001872, Deinococcus gene (DR0093), Nov. 22, 1999.
P.C. Lee et al., Metabolic Engineering Towards Biotechnological Production Of Carotenoids In Microorganisms, Appl. Microbiol. Biotechnol., 2000, pp. 1-11, vol. 60.
Cheng Qiong
Tao Luan
E. I. du Pont de Nemours and Company
Patterson Jr. Charles L.
LandOfFree
Carotenoid ketolase gene does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Carotenoid ketolase gene, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Carotenoid ketolase gene will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3536695