Carotenoid hydroxylase enzymes

Details Carotenoid hydroxylase enzymes Carotenoid hydroxylase enzymes

2006-08-15

2006-08-15

Prouty, Rebecca E. (Department: 1652)

Chemistry: molecular biology and microbiology

Micro-organism, per se ; compositions thereof; proces of...

Bacteria or actinomycetales; media therefor

C435S189000, C435S320100, C435S254100, C435S255100, C435S419000, C435S411000, C435S412000, C435S414000, C435S415000, C435S252100, C435S252310, C435S252320, C435S252330, C435S252340, C435S252350, C435S254210, C435S254220, C435S254230, C435S254300, C435S254600, C435S257200, C536S023200

Reexamination Certificate

active

07091031

ABSTRACT:
A novel CrtZ carotenoid hydroxylase, isolated fromBrevundimonas vesicularisDC263, is provided that is useful for the production of hydroxylated carotenoids. Additionally, a previously identified hypothetical protein fromNovosphingobium aromaticivoranshas found to have carotenoid hydroxylase activity. Both hydroxylase genes exhibit low homology in comparison to other CrtZ hydroxylases previously reported. Expression of the hydroxylases in heterologous host cells enabled production of hydroxylated carotenoids.

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