Carnitine derivatives, process for their preparation, and their

Details Carnitine derivatives, process for their preparation, and their Carnitine derivatives, process for their preparation, and their

1990-05-03

1993-11-09

Dees, Jose G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Fatty compounds having an acid moiety which contains the...

554 79, C07F 902

Patent

active

052604640

ABSTRACT:
New carnitine derivatives are described having the formula (I): ##STR1## wherein A=H, --(CH.sub.2).sub.n --O--CO--R.sub.1, n being 1 or 2, and B=--(CH.sub.2).sub.m --O--CO--R.sub.2, m being 1, 2, 3, or 4 with the limitation that when A=--(CH.sub.2).sub.n --O--CO--R.sub.1, m is 1 or 2, and in which R.sub.1 and R.sub.2, equal or different are radicals of aliphatic, aromatic, araliphatic, alicyclic or heterocyclic acids.
The process for preparing said derivatives is also described and their use in the therapy of human pathologies associated with neuronal damages.

REFERENCES:
patent: 5008288 (1991-04-01), Stracher et al.
Chemical Abstracts, vol. 82, #21, 1985, p, 134462d.
Eibl et al., Biochemica et Biophysica Acta, vol. 553, pp. 476-488, 1979.

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