Carminomycin derivatives, their preparation and use

Details Carminomycin derivatives, their preparation and use Carminomycin derivatives, their preparation and use

1978-01-26

1980-02-12

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 17A, A61K 3170, C07H 1524

Patent

active

041883772

ABSTRACT:
N-acyl derivatives of the known antitumor antibiotic carminomycin, particularly N-trifluoroacetyl carminomycin, have a much lower toxicity than carminomycin.

REFERENCES:
patent: 4035566 (1977-07-01), Israel et al.
Kendo, et al. "Jour. Amer. Chem. Soc.", vol. 98, Mar. 31, 1976, pp. 1967-1969.

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