Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1991-07-24
1993-03-30
Bond, Robert T.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546157, C07D215227
Patent
active
051984482
ABSTRACT:
Method for prophylaxis and treatment of heart diseases using a carbostyril derivative of formula: ##STR1## wherein R.sup.1 is H or CN, and R.sup.2 and R.sup.3 are each H, alkyl optionally substituted by OH, cycloalkyl, alkenyl, phenyl, phenylalkyl having optionally substituents of alkoxyalkoxy, halogen, alkoxy, NO.sub.2, alkyl, CN, alkylthio or alkylsulfinyl on phenyl ring and having optionally OH-substituent on alkyl moiety, phenylsulfonylalkyl having optionally alkoxy substituent on phenyl ring, phenylthioalkyl, phenylsulfinylalkyl having optionally substituents of halogen or alkoxy on phenyl ring, phenoxyalkyl having optionally substituents of halogen or alkoxy on phenyl ring, pyridylalkyl having optionally substituents of halogen or alkoxy on pyridine ring, thienylalkyl, benzoylalkyl, anilinothiocarbonyl, benzoyl, pyridyl, phenylalkenyl, or group of --A-NR.sup.4 R.sup.5 (R.sup.4 and R.sup.5 are each alkyl or phenyl having optionally substituents of halogen or alkoxy on phenyl ring, and A is alkylene which may be interrupted with O), and a salt thereof, and novel carbostyril derivatives, and pharmaceutical composition for prophylaxis and treatment of heart diseases containing said novel carbostyril derivative.
REFERENCES:
patent: 4210753 (1980-07-01), Tominaga et al.
patent: 4309432 (1982-01-01), Tanaka et al.
patent: 4652672 (1987-03-01), Linder
patent: 4914093 (1990-04-01), Morisawa et al.
patent: 5015638 (1991-05-01), Spada et al.
patent: 5053514 (1991-10-01), Fujioka et al.
Fujioka Takafumi
Teramoto Shuji
Tominaga Michiaki
Yabuuchi Yoichi
Bond Robert T.
Otsuka Pharmaceutical Company Limited
Ward E. C.
LandOfFree
Cardiotonics does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Cardiotonics, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cardiotonics will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1281234