Cardiotonic 4-aroylimidazolidin-2-ones

Details Cardiotonic 4-aroylimidazolidin-2-ones Cardiotonic 4-aroylimidazolidin-2-ones

1981-11-04

1983-10-18

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

4242485, 42424857, 424250, 424267, 544139, 544370, 546210, 548318, 548321, A61K 31415

Patent

active

044105401

ABSTRACT:
This invention relates to aroyl-2-imidazolidinones of the following general structure which are useful as cardiotonics and antihypertensive agents ##STR1## wherein Ar is furanyl, thienyl, 1H-pyrrolyl, or phenyl optionally substituted with one or two X groups; X is halogen, hydroxy, lower alkyl, lower alkoxy, lower alkylthio, lower alkylsulfoxide, lower alkylsulphone, trifluoromethyl, --SO.sub.2 N(R.sub.2).sub.2, NR.sub.3 R.sub.4, pyrrolidino, piperidino, morpholino, piperazino or N'-alkyl-piperazino; R is hydrogen, lower alkyl, lower alkylcarbonyl or benzoyl; each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is hydrogen or lower alkyl; T is an oxygen atom or a divalent sulfur atom; and the pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 3337580 (1967-08-01), Lunsford et al.
Chemical Abstracts, 90:64361j (1979) [Endo, T., et al., JPN. Kokai Tokkyo Koho 78 52,422, 5/12/78].
Chemical Abstracts, 87:152201a (1977) [Miyoshi, M., et al., Japan, Kokai 77 46,074, 4/12/77].

Affiliated with

Also associated with

Rating

Cardiotonic 4-aroylimidazolidin-2-ones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cardiotonic 4-aroylimidazolidin-2-ones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cardiotonic 4-aroylimidazolidin-2-ones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1289398