Cardiopulmonary bypass and organ transplant using a potassium ch

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

514456, 514255, 514392, 5142355, 514337, 540484, A61K 3144, A61K 3135, A61K 31495, A61K 31535

Patent

active

056439210

ABSTRACT:
In accordance with the present invention novel methods for cardiopulmonary bypass and organ transplant, each employing a potassium channel activator, are disclosed. The use of a potassium channel activator has been found to reduce the damage or ischemia induced by the bypass and transplant procedures.

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F. Gharagozloo et al., J. of Thoracic and Cardiovascular Surgery, vol. 77, No. 4, Apr. 1979, pp. 602-607.
F. Gharagozloo et al., Cardiac Transplantation, vol. 76, (supp V), Nov. 1987, pp. V-65 to V-70.
H. Kohno et al., J. Thorac. Cardiovasc. Surg., vol. 93, No. 1, Jan. 1987, pp. 86-94.
GA: vol. 105 (1986): 91027(8) Sakamoto.

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