Cardiac steriod glycosides

Details Cardiac steriod glycosides Cardiac steriod glycosides

1992-06-12

1993-12-14

Husarik, Nancy S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

540106, 552557, 552582, C07J 4100, A61K 31705

Patent

active

052704572

ABSTRACT:
14.beta.-hydroxy-3.beta.-(.alpha.-L-rhamnopyranosyl) and-tridigitoxide-oxy-20-nitro-21-nor-5.beta.,14.beta.-pregnanes exhibit unexpectedly high cardiac potency with tolerance to high dosage levels.

REFERENCES:
patent: 4882315 (1989-11-01), Chiodini et al.
patent: 5144017 (1992-09-01), LaBella et al.
Lucas et al; J. Am. Chem. Soc. 82:5688-5693 (1960).
Katzung et al; Experientia 26(11):1189-91 (1970).
Eberlein et al; Chem. Ber. 107:1275-1284 (1974).
Rohrer et al; J. Am. Chem. Soc. 98(20):6308-6312 (1976).
Kim et al; Molecular Pharmacology 18:402-405 (1980).
Brown et al; Arznei M. Forsch./Drug Res. 31(II), No. 7:1059-1064 (1981).
Templeton et al; Can. J. Physiol. Pharmacol. 66:1420-1424 (1988).

Affiliated with

Also associated with

Rating

Cardiac steriod glycosides does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Cardiac steriod glycosides, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Cardiac steriod glycosides will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1706917