Cardiac muscle regeneration using mesenchymal stem cells

Details Cardiac muscle regeneration using mesenchymal stem cells Cardiac muscle regeneration using mesenchymal stem cells

2011-02-22

2011-02-22

Hama, Joanne (Department: 1632)

Chemistry: molecular biology and microbiology

Animal cell, per se ; composition thereof; process of...

Method of regulating cell metabolism or physiology

C435S325000, C435S372000

Reexamination Certificate

active

07892829

ABSTRACT:
Disclosed is a method for producing cardiomyocytes in vivo by administering to the heart of an individual a cardiomyocyte producing amount of mesenchymal stem cells. These cells can be administered as a liquid injectable or as a preparation of cells in a matrix which is or becomes solid or semi-solid. The cells can be genetically modified to enhance myocardial differentiation and integration. Also disclosed is a method for replacing cells ex vivo in a heart valve for implantation.

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