Cardiac glycoside or aglycone assays

Details Cardiac glycoside or aglycone assays Cardiac glycoside or aglycone assays

1976-04-08

1977-11-01

Padgett, Benjamin R.

Drug, bio-affecting and body treating compositions

Radionuclide or intended radionuclide containing; adjuvant...

Molecular bilayer structure

23230B, 424 12, G01N 3300, G21H 502

Patent

active

040566080

ABSTRACT:
Immunoassays for digoxin and its congeners are provided by pre-treating the serum sample with dilute aqueous alkaline solutions under mild conditions and for short periods of time, preferably in combination with a chelating agent, prior to carrying out the immunoassay. The method finds particular application with radioimmunoassays and homogeneous enzyme immunoassays.

REFERENCES:
patent: 3855208 (1974-12-01), Rutner et al.
patent: 3925355 (1975-12-01), Piasio et al.
patent: 3933997 (1976-01-01), Hersh et al.
patent: 3975511 (1976-08-01), Vann et al.
Wong, Clinical Chemistry, vol. 21, No. 2, 1975, pp. 216-220.
Oliver et al., Journal of Clinical Investigation, vol. 47, No. 5, May, 1968, pp. 1035-1042.

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