Surgery – Truss – Pad
Patent
1987-10-26
1989-04-11
Jaworski, Francis
Surgery
Truss
Pad
128419P, A61N 100
Patent
active
048196622
ABSTRACT:
An implantable cardiac pacing lead includes a porous, platinum electrode, a flexible electrically conductive coil, and a crimp tube coupling the electrode to the distal end of the coil. A recess in the crimp tube, open to the electrode at the crimp tube distal end, houses a matrix impregnated with a therapeutic drug. The electrode is highly porous and loaded with a therapeutic drug in liquid or solid form. Immediately upon implant of the electrode at a selected myocardial location, the electrode begins dispensing the therapeutic drug. Meanwhile, the matrix begins to elute its drug at a rate more suited to chronic treatment. If desired, the recess can extend through the crimp tube to permit proximal end loading of the drug carrying matrix. A silicone plug, or an additional and proximal crimp tube section, is inserted into the recess after loading of the matrix to provide the required fluid seal. Finally, a variety of different matrices can be housed in the recess, to provide elution of different drugs and at differing rates.
REFERENCES:
patent: 4360031 (1982-11-01), White
patent: 4418704 (1983-12-01), Theisen et al.
patent: 4506680 (1985-03-01), Stokes
patent: 4577642 (1986-03-01), Stokes
patent: 4606118 (1986-07-01), Cannon et al.
patent: 4711251 (1987-12-01), Stokes
Heil, Jr. Ronald W.
Owens Robert C.
Pederson Brian D.
Cardiac Pacemakers Inc.
Haugen Orrin M.
Jaworski Francis
Manuel George
Niebuhr Frederick W.
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