Cardiac drug delivery system

Details Cardiac drug delivery system Cardiac drug delivery system

2006-09-12

2006-09-12

Mercader, Eleni Mantis (Department: 3737)

Surgery

Instruments

Electrical application

C607S003000, C607S120000

Reexamination Certificate

active

07104988

ABSTRACT:
A system is disclosed, for administering a therapeutic agent locally and to a depth within cardiac tissue. An elongate, flexible catheter contains a flexible electric conductor and supports at its distal end an implantable electrode incorporating a penetrating element, typically a fixation helix or a linear needle that penetrates cardiac tissue as the electrode is implanted. A therapeutic agent is delivered through the electrode, to the cardiac tissue surrounding the penetrating element. The electrode can act as a sensor, to monitor an electrical condition of the surrounding cardiac tissue, and to control delivery of the agent responsive to the sensed electrical condition. Several embodiments feature a distal reservoir adjacent the electrode for effecting transient deliveries of the therapeutic agent in minute quantities. Other embodiments are disclosed for providing sustained deliveries of the agents.

REFERENCES:
patent: 6086582 (2000-07-01), Altman et al.
patent: RE37463 (2001-12-01), Altman
patent: 6358247 (2002-03-01), Altman et al.

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