Carcinostatic or antitumor antibiotic, conagenin, and production

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Radical -xh acid – or anhydride – acid halide or salt thereof...

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435106, 4352535, 562567, A61K 31195

Patent

active

050989359

ABSTRACT:
A new antibiotic, named Conagenin, is provided which can exhibit useful carcinostatic or antitumor activities on carcinomas and tumors, particularly malignant tumors, of mammalian animals including man. Conagenin can be produced by fermentation of microorganisms of genus Streptomyces, typically Streptomyces roseosporus MI696-AF3 strain identified under the deposit number FERM BP-2738. Conagenin has formula (I) and is useful for medicinal purposes, particularly as carcinostatic agent or antitumor agent for inhibiting carcinomas and malignant tumors of mammalian animals, including man.

REFERENCES:
patent: 2856421 (1958-10-01), Hasbrouck
patent: 3856854 (1974-12-01), Schnettler

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