Carboxyvinyl polymer having Newtonian viscosity

Drug – bio-affecting and body treating compositions – Topical body preparation containing solid synthetic organic... – Ophthalmic preparation

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424 7831, 514915, 522 86, 522153, 523318, 523300, A61K 4732, C08J 328

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active

054588731

ABSTRACT:
A carboxyvinyl polymer having Newtonian viscosity, ophthalmic preparations containing the polymer, a process for preparing the polymer, and a vehicle for ophthalmic preparations containing the polymer. By using the polymer in a vehicle, an ophthalmic preparation having a low viscosity and a desirable permeability of a drug can be obtained.

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patent: 5192535 (1993-03-01), Davis et al.
N. Unlu et al; "Formulation of Carbopol 940 Opthalmic Vehicles, and in vitro evaluation of the Influence of Simulated Lacrimal Fluid on their Physico-Chemical Properties"; Die Pharmazie; vol. 46; No. 11, Nov. 1991; pp. 784-788.
Derwent Publications Ltd.; Database WPIL; & JP-A-60-235815; (Sansui Denki KK); Nov. 1985 Abstract.
United States Pharmacopoeia, "Carbomer 910", issued 1989, p. 1910.
Japanese Standards of Pharmaceutical Ingredients 1991 Part II, "Carboxyvinyul Polymer", pp. 1177-1180.

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