Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-11-17
1999-11-02
Chang, Ceila
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
5142278, 5142355, 5142362, 514255, 514318, 514326, 544 60, 544129, 544364, 546187, 546193, 546208, 546210, A01N 4340
Patent
active
059771399
ABSTRACT:
The present invention relates to novel carboxy substituted cyclic carboxamide derivatives of formula (1), ##STR1## and stereoisomers and pharmaceutically acceptable salts thereof and their use as tachykinin receptor antagonists. Such antagonists are useful in the treatment of tachykinin-mediated diseases and conditions disclosed herein including: asthma, coughs and bronchitis.
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Burkholder Timothy P.
Kudlacz Elizabeth M.
Maynard George D.
Chang Ceila
Hoechst Marion Roussel Inc.
Stemerick David M.
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