Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving nucleic acid
Patent
1997-06-09
1999-02-09
Chan, Christina Y.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving nucleic acid
435 692, 43525233, 4353201, 514 12, 530350, 530412, 536 235, 536 2431, C12Q 168, C12N 1557, C12N 1511, C07H 2104
Patent
active
058692592
ABSTRACT:
The invention provides a human carboxypeptidase inhibitor (CARIN) and polynucleotides which identify and encode CARIN. The invention also provides expression vectors, host cells, agonists, antibodies and antagonists. The invention also provides methods for treating disorders associated with expression of CARIN.
REFERENCES:
Hillier, et al. GenBank Accession #WO4874, Apr. 23, 1996.
Hillier, et al., Gen Bank Accession #WO1258, Apr. 18, 1996.
Alberts B, Bray D, Lewis J, Raff M, Roberts K, and Watson JD Molecular Biology of the Cell, Garland Pub. New York, NY, pp. 189-191, 1983.
Normant, E. et al., "Carboxypeptidase A Isoforms Produced by Distinct Genes or Alternative Splicing in Brain and Other Extrapancreatic Tissues", J. Biol. Chem., 270: 20543-20549 (1995).
Normant, E. et al., "Purification, cDNA cloning, functional expression, and characterization of a 26-kDa endogenous mammalian carboxypeptidase inhibitor", Proc. Natl. Acad. Sci., 92: 12225-12229 (1995) (GI 1101779; GI 1101780).
Hatanaka, Y. et al., "Intracortical Regionality Represented by Specific Transcription for a Novel Protein, Latexin", Eur. J. Neurosci., 6: 973-982 (1994).
Jin, M. et al., (Direct Submission), GenBank Sequence Database (Accession D88769), National Center for Biotechnology Information, National Library of Medicine, Bethesda, Maryland, 20894 (GI 1669620; GI 1669621) (Nov. 1996).
Hillman Jennifer L.
Lal Preeti
Billings Lucy J.
Chan Christina Y.
Incyte Pharmaceuticals Inc.
Price Leanne C.
Tung Mary Beth
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