Carboxylic compound and medicine comprising the same

Details Carboxylic compound and medicine comprising the same Carboxylic compound and medicine comprising the same

2006-09-19

2006-09-19

Richter, Johann (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

C514S557000, C514S559000, C514S866000, C554S215000

Reexamination Certificate

active

07109242

ABSTRACT:
A compound represented by the following general formula (1), a salt thereof, or an ester thereof:wherein m represents an integer of 0 to 4, n represents an integer of 5 to 9, and R represents hydrogen atom or a protective group of hydroxyl group, which has reducing actions of blood glucose, plasma insulin, and triglyceride, and is useful for preventive and/or therapeutic treatment of diabetes, complications of diabetes, hyperlipemia and others.

REFERENCES:
patent: 5968982 (1999-10-01), Voss et al.
patent: 5-952 (1993-01-01), None
patent: 10-510515 (1998-10-01), None
English Language Abstract of JP 5-952.
Expert Opinion on Investigational Drugs, “Insulin Sensitiser Drugs,” vol. 9, No. 6, pp. 1347-1361, 2000.
European Journal of Medicinal Chemistry, “ω-Substituted Alkyl Carboxylic Acids As Antidiabetic and Lipid-Lowering Agents,” vol. 33, pp. 775-787, 1998.
Metabolism, “BM 17.0744: A Structurally New Antidiabetic Compound With Insulin-Sensitizing and Lipid- Lowering Activity,” vol. 48, No. 1, pp. 34-40, Jan. 1999.
Journal of Medicinal Chemistry, “The Effect of 1,3-Diaryl-[1H]-pyrazole-4-acetamides on Glucose Utilization in ob/ob Mice,” vol. 44, pp. 2601-2611, Jul. 6, 2001.
Journal of Clinical Investigation, “Glucose Transporter Levels in Spontaneously Obese(db/db)Insulin-resistant Mice,” vol. 85, pp. 962-967, Mar. 1990.
Arznimittel-Forschung, “Effects of Pioglitazone on Glucose and Lipid Metabolism in Normal and Insulin Resistant Animals,” vol. 40, pp. 156-162, 1990.
Archives of Toxicology, “Species Differences in Induction of Hepatic Enzymes by BM 17.0744, An Activator of Peroxisome Proliferator-Activated Receptor Alpha(PPARα),” vol. 73, pp. 440-450, 1999.

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