Carboxylic acid substituted heterocycles, derivatives...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C540S482000

Reexamination Certificate

active

06838454

ABSTRACT:
Selected novel carboxylic acid substituted heterocycle compounds are effective for prophylaxis and treatment of inflammation, tissue degradation, cancer, fibrosis and related diseases. The invention encompasses novel compounds, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of inflamation, tissue degradation and related diseases. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

REFERENCES:
patent: 039051 (1985-07-01), None
patent: 606046 (1994-07-01), None
patent: 803505 (1997-10-01), None
patent: WO 9629313 (1996-09-01), None
patent: WO 9633172 (1996-10-01), None
patent: WO 9718194 (1997-05-01), None
Gibson et al., J Org. Chem., 59:3216 (1994), “Selective Removal of an N-Boc Protecting Group in the Presence of tert-Butyl Ester and Other Acid-Sensitive Groups”.
Svensson et al., Drug Metabolism r Reviews, 19(2), 165-194 (1988), “The Design and Bioactivation of Presystemically Stable Prodrugs”.
Bundgaard, J. Med. Chem., 32(12), 2503 (1989), “A Novel Solution-Stable, Water-Soluble Prodrug Type for Drugs Containing a Hydroxyl or an NH-Acidic Group”.
Baldwin et al., Tetrahedron, 45(19), 6309 (1989), “Non-Proteinogenic Amino Acid Synthesis”.
Schuster et al., Angew. Chem Inst. Ed. Engel, 36: 2036-2056 (1997), “Olefin Metathesis in Organic Chemistry”.
Ninomiya et al., Tetrahedron, 30: 2151 (1974), “Phosphorus in Organic Synthesis-VIII”.
Wadsworth, Organic Reactions, 25: 73-253 (1977), Chapter 2, “Organic Reactions”.
Rabjohn, Organic Reactions, 24: 261-415 (1976), Chapter 4, “Organic Reactions”.
Nagasawa et al., J. Med. Chem., 14(6), 501-508 (1971), “Medium Ring Homologs of Proline as Potential Amino Acid Antimetabolites”.

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