Carboxylic acid reductase polypeptide, nucleotide sequence...

Details Carboxylic acid reductase polypeptide, nucleotide sequence... Carboxylic acid reductase polypeptide, nucleotide sequence...

2006-05-10

2008-09-16

Pak, Yong D (Department: 1652)

Chemistry: molecular biology and microbiology

Enzyme , proenzyme; compositions thereof; process for...

Oxidoreductase

C435S440000, C435S025000, C435S069100, C435S071100, C435S132000, C536S023200

Reexamination Certificate

active

07425433

ABSTRACT:
The invention provides the nucleotide sequence and amino acid sequence for the enzyme carboxylic acid reductase isolated from bacteria. Expression cassettes, vectors, transformed cells, and variants are also provided as methods for use of recombinant biocatalytic reagents in production of synthetic, aromatic, aliphatic and alicyclic aldehydes and alcohols.

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Cole et al. Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence.□□Nature. Jun. 11, 1998;393(6685):537-44. Erratum in: Nature Nov. 12, 1998;396(6707):190.
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Branden et al. Introduction to Protein Structure, Garland Publishing Inc., New York, p. 247, 1991.
Kita et al. “Cloning of the aldehyde reductase gene from a red yeast,Sporobolomyces salmonicolor, and characterization of the gene and its product.” Appl. Environ. Microbiol. Jul. 1996;62(7):2303-10.
Venkitasubramanian et al., “Reduction of Carboxylic Acids by Nocardia Aldehyde Oxidoreductase Requires a Phosphopantetheinylated Enzyme”, J. of Biol. Chem., 282(1)P478-485 (2007).

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